ch 16: cholinergics Flashcards
what system is cholinergic dealing with? what does it bind to?
- parasympathetic
- acetylcholine
what are parasympathomimetics?
drugs that mimics the parasympathetic NS
what does bethanechol do? why do you not give IV? adverse reactions?
- stimulates muscularinic receptors to increase urine output
- too much will cause overdose
- orthostatic hypotension and bradycardia
what do in-direct cholinergic drugs do?
inhibit enzyme cholinesterase
what are reversible cholinesterase inhibitors use for? what does it do?
- myasthenia gravis
- increases muscular strength
what is the antidote used for irreversible cholinesterase inhibitors?
pralidoxime chloride
what is the antidote used for reversible cholinesterase inhibitors?
pyridostigmine
what is atropine used for?
- preoperative med to decrease salivary and respiratory secretions
- antispasmodic
- antidote for muscarinic agonist poisening
- bradycardia
what is atropine used for?
- preoperative med to decrease salivary and respiratory secretions
- antispasmodic
- antidote for muscarinic agonist poisening
- bradycardia
what are the cholinergic overdose symptoms? what is the antidote? what does this result in?
- SLUDGE
- salivation
- lacrimation
- urinary incontinence
- diarrhea
- emesis
- atropine
- bradycardia
what are anticholinergic overdose symptoms? what are the antidote? what does this result in?
- dry mouth
- urinary retention
- drowsiness
- dizziness
- blurred vision
- physostigmine and salicylate
- tachycardia
what can be used to treat parkinson’s? what does it do?
- anticholinergic
- treats drooling and salivation
how is anticholinergics used for treating motion sickness?
- scopolamine
- patch behind the ear
