Ch 21 Pharmacology Flashcards
new drug synthesis
medicinal chemistry
drug effects on the body
pharmacodynamics
drug’s absorption, distribution metabolism, and excretion over time
pharmacokinetics
interaction of drugs and components inside the cell or on the cell surface
molecular pharmacology
use of drugs in treatment of cancer and infectious disease
chemotherapy
studies of harmful effects of drugs on the body
toxicology
administration of drugs by mouth
oral administration
administration of drugs placed under the tongue that dissolve in saliva
sublingual
administration of drugs inserted into the rectum
rectal
administration of drugs where there is an injection of drug from a syringe through a hollow needle placed under the skin, into a muscle, vein or body cavity
parenteral administration
parenteral administration injection is made into a body cavity such as the peritoneal or pleural cavity
intercavitary instillation
parenteral administration occurs in the space under the membranes surrounding the spinal cord and brain
intrathecal instillation
administration of drugs taken into the nose or moth and absorbed into the bloodstream through the thin walls of air sacs in the lungs
inhalation
administration of drugs where particles of drugs suspended in air are administered by inhalation
aerosols
administration of drugs applied locally on the skin or mucous membranes of the body
topical application
2 topical drugs commonly used as ointments, creams and lotions
- antiseptics
2. antipruritics
patches used to deliver drugs continuously through the skin
transdermal patches
3 oral vehicles for administration
- caplets
- capsules
- tablets
1 sublingual vehicle for administration
tablets
1 rectal vehicle for administration
suppositories
2 parenteral vehicles for administration
- injections
2. instillations
7 types of injections and instillations
- intracavitary
- intradermal
- intramuscular
- intrathecal
- intravenous
- pumps
- subcutaneous
1 vehicle for inhalation administration
aerosols
4 vehicles for topical administration
- lotions
- creams
- ointments
- transdermal patches
drug family that lessens pain
analgesics
drug family that reduces or eliminates sensation
anesthetic
drug family: chemical substance produced by a microorganism that inhibits or kills bacteria, fungi or parasites
antiobiotics and antivirals
microorganism that inhibits bacteria, fungi, or parasites
bacteriostatic
microorganism that kills bacteria, fungi, or parasites
bactericidal
drug family that treats fungal infections
antifungal
drug family that prevents clotting or coagulation of blood
anticoagulants and antiplatelet
drug family that prevents or reduces frequency of convulsions in various types of seizure disorders or epilepsy
anticonvulsants
drug family that treat symptoms of depressions; also mild sedatives
antidepressants
drug family that treats symptoms of Alzheimer disease by aiding brain neurotransmitters or shielding brain cells from glutamate
anti-Alzheimer drugs
drug family used to treat diabetes mellitus
antidiabetics
drug family that blocks the action of histamine, which is normally released in the body in allergic reactions
antihistamines
drug family that prevent nausea; used to prevent motion sickness
antiemetic
drug family that act on the heart or the blood vessels to treat hypertension, angina, MI, CHF and arrhythmias
cardiovascular drugs
drug family that dilate blood vessels to lower blood pressure, improving the performance of the heart, and reduce workload
angiotensin-convering enzyme (ACE) inhibitors
drug family that lower blood pressure by preventing angiotensin from acting on receptors in blood vessels
angiotensin II receptor blockers (ARBs)
drug family that reverse abnormal heart rhythms
antiarrhythmics
drug family that decrease muscular tone in blood vessels, slow heart rate, decrease heart output, reduce blood pressure by blocking the action of epinephrine at receptor sites in the heart/blood vessels
beta blockers
drug family that dilates blood vessels and lower blood pressure and treat angina and arrhythmias
calcium channel blockers
drug family that increase the force of contraction of the heart; treats heart failure and atrial fibrillation
cardiac clycosides
drug family that bind to dietary cholesterol and prevent its uptake from the GI tract
cholesterol binding drugs
drug family that control hypercholesterolemia
cholesterol lowering drugs (statins)
drug family that reduces volume of blood in the body by promoting the kidney to remove water and salt through urine
diuretics
drug family that interfere with the production of androgens or with their binding in tissues
antiandrogens
drug family that reduce amount of estrogen in the blood; effective against cancer
aromatase inhibitors
drug family that have estrogen like effects on bone and lipid metabolism
selective estrogen receptor modulators (SERMs)
drug family that neutralize hydrochloric acid in the stomach to relieve symptoms of peptic ulcer, esophagitis and reflux
antacids
drug family that blocks secretion of acid by cells in the lining of the stomach
antiulcer
drug family that treat autoimmune diseases such as Crohn’s
anti-tnf tumor necrosis factor
drug family that open bronchial tubes and are administered by injection or aerosol inhalers
bronchodilators
drug family that are inhaled or given IV and orally to reduce chronic inflammation in respiratory passageways
steroid drugs
drug family that prevent asthma attacks by blocking leukotriene from binding to receptors in respiratory tissues
leukotriene modifiers
drug family that depress the CNS ad promote drowsiness and sleep
sedative-hypnotics
2 major categories of sedative hypnotics
- barbitruates
2. benzodiazepines
drug family that act on the brain to speed up vital processes in cases of shock and collapse
stimulants
drug family that control anxiety
tranquilizers
hormone from the adrenal cortex that raises blood sugar and reduces inflammation
glucocorticoid
aer/o
air
alges/o
sensitivity to pain
bronch/o
bronchial tube
chem/o
drug
cras/o
mixture
cutane/o
skin
derm/o
skin
erg/o
work
esthes/o
feeling, sensation
hist/o
tissue
hypn/o
sleep
iatr/o
treatment
lingu/o
tongue
myc/o
mold, fungus
narc/o
stupor
or/o
mouth
pharmac/o
drug
prurit/o
itching
pyret/o
fever
thec/o
sheath (of brain and spinal cord)
tox/o
poison
toxic/o
poison
vas/o
vessel
ven/o
vein
vit/o
life
ana-
upward, excessive, again
anti-
against
contra-
againts, opposite
par-
other than, apart from
syn-
together, with
ac
before meals (ante cibum)
bid
2 times a day
h
hour
hs
at bedtime
IM
intramuscular
IV
intravenous
npo
nothing by mouth (nil per os)
NSAID
nonsteroidal anti-inflammatory drug
pc
after meals (post cibum)
PCA
patient controlled analgesia
prn
as needed; as necessary
q
every
qh
every hour
q2h
every 2 hours
qid
4 times a day
Rx
prescription
tid
3 times daily
high cholesterol drugs
atorvastatin (Lipitor)
hypothyroidism drugs
levothyroxine (Synthroid)
coronary artery disease drugs
clopidogrel bisulfate (Plavix)
a. bacterial infections drugs
cephalexin (Keflex)
b. bacterial infections drugs
levofloxacin (Levaquin)
c. bacterial infections drugs
tetracycline
epilepsy drugs
phenytoin sodium (Dilantin)
depression drugs
fluoxetine (Prozac)
alzheimer drugs
donepezil (Aricept)
hay fever drugs
loratadine (Claritin)
osteoporosis drugs
alendronate (Fosamax)
prostate cancer drugs
flutamide (Eulexin)
fungal infection drugs
terbinafine (Lamisil)
thrombosis drugs
warfarin (Coumadin)
GERD drugs
ranitidine (Zantac)
diarrhea drugs
loperamide (Imodium)
Crohn’s drugs
adalimumab (Humira)
asthma drugs
albuterol (Ventolin)
prostate cancer drugs
flutamide (Eulexin)
breast cancer drugs
tamoxifin (Nolvadex)
allergic drugs
prednisone (Deltasone)
insomia drugs
zolpiderm tartrate (Ambien)
ADD drugs
methylphenidate (Ritalin)
- anxiety drugs
lorazepam (Ativan)
- anxiety drugs
diazepam (Valium)