Ch 2 - Abnormalities of Teeth 2 Flashcards
How much of the tooth root is formed when emergence through the gingiva occurs?
2/3s of the root is developed
What are 3 “local” conditions associated with delayed eruption?
- supernumerary teeth 2. Regional odontodysplasia 3. Segmental Odontomaxillary Dysplasia
What are 3 “systemic” conditions associated with delayed eruption?
- Anemia 2. Celiac Dz 3. Cerebral palsy
Some authors subdivide these non-erupted teeth into those that are obstructed by a physical barrier (impacted) and those that appear to exhibit a lack of eruptive force (________).
embedded
Impaction of deciduous teeth is extremely rare, when it is seen which teeth are most likely involved? What pathologic process is most commonly the cause?
second molars…ankylosis
HOLY S! One review of 2646 pericoronal lesions submitted to an active oral pathology service revealed that ___% of cases had pathologically significant lesions! A good reason to get them taken out…
32.9%
infraocclusion, secondary retention, submergence, reimpaction, and reinclusion are all terms for:
ankylosis
What is the most common tooth to have ankylosis?
mandibular primary first molar
What is the difference between hypodontia and oligodontia?
Hypo: 1 or more teeth…Oligo: 6 or more teeth excluding 3rd molars
How many genes are involved in odontogenesis?
more than 200
What are the 7 implicated genes in hypodontia?
- PAX9
- MSX1
- AXIN2
- He-Zhao
- LTBP3
- EDA
- WNT10A
What are 5 syndromes (out of 39) associated with hypodontia?
- Down 2. Ectodermal Dysplasia 3.Ehlers-Danlos 4.Gorlin 5.Otodental dysplasia
What are 5 syndromes (out of 20) associated with hyperdontia?
- Apert 2. Cleidocranial Dysplasia 3.Gardner 4.Down 5. Leopard
Failure of teeth to form is one of the most common dental developmental abnormalities, with a reported prevalence of ___-___% in permanent teeth when absence of third molars is excluded. The prevalence increases to __% if third molars are considered.
3% to 10%…20%
Hypodontia gender predominance?
A female predominance of approximately 1.5 : 1 is reported.
Anodontia is rare with most cases arising from which condition?
hereditary hypohidrotic ectodermal dysplasia
Which 3 teeth are LEAST likely to be congenitally missing?
max central incisors, mand first molars, mand canines
In the deciduous dentition, 90% of missing teeth involve the _______ and _______
maxillary lateral incisors and mandibular incisors
Mutation of the PAX9 gene creates an ___ pattern of oligodontia that can involve various teeth but most commonly affects WHICH TEETH?
AD…permanent molars
Mutation of the MSX1 gene also is inherited as an
_____ trait. Those affected with this mutation
tend to demonstrate loss of the distal tooth of each
type, with more severely affected individuals also revealing anterior progression of the agenesis. In these patients, the most commonly missing teeth are the ________ and _______
AD…second premolars and third molars
Which hypodontia gene mutation is associated with and average of approximately 12 missing teeth?
MSX1
Which hypodontia gene deficiency was discovered in a large kindred from northwest China?
He-Zhao
Which hypodontia gene mutation was discovered in a Pakistani lineage?
LTBP3
The _____ gene is associated with a nonsyndromic X-linked pattern of hypodontia, which primarily affects the maxillary and mandibular central incisors, lateral incisors, cuspids, and premolars.
EDA (ANTERIOR TEETH most affected)