Ch 15B (pt.1): TA Review Flashcards
What are the types of feedback regulation?
Positive feedback
Negative feedback
What is positive feedback?
A loop where a stimulus causes the perpetuation of an end result.
What is a negative feedback?
A loop where a stimulus causes the eventual termination of a result.
What feedback regulation has an active loop?
Positive feedback
What feedback regulation has an inactive loop?
negative feedback
Which feedback regulation downstream response suppresses the signal?
Negative feedback
Which feedback regulation downstream response enhances the signal?
Positive feedback
When referring to cell sensitivity, adaptation….
Responds to various types of stimuli and environmental changes
When referring to cell sensitivity desensitization….
Prolonged exposure to a stimulus decreases the cells response to a stimulus
Responds to various types of stimuli and environmental changes.
A. Adaptation
B. Desensitization
A. Adaptation
Prolonged exposure to a stimulus decreases the cell’s response to a stimulus.
A. Adaptation
B. Desensitization
B. Desensitization
GPCR’s are 7-pass transmembrane proteins, which side of the receptor will bind to a G protein?
Cytoplasmic side
Where will molecules that GPCRs recognize to be small bind?
bind DEEP into a pocket of the receptor
GDP is bound to the active site of:
A. Active G protein
B. Active GPCR
C. Inactive G protein
D. Inactive GPCR
C. Inactive G protein
Inactive G-protein has ____ bound to the active site.
A. GTP
B. GDP
C. GEF
D. GAP
B. GDP
Activated GPCR G-protein stimulates the exchange of____ for____.
A. GDP, GTP
B. GTP, GDP
C. GEF, GAP
D. GAP, GEF
A. GDP, GTP
G-protein will dissociate from what when activated?
dissociates from GPCR and Beta-gamma complex
What is the regulator for G-protein signaling?
alpha-subunit
All or nothing respinses in frog oocytes is due to the positive feedback from what hormone?
progesterone
Enzymes activated by G-protein will do what to second messengers?
Amplify the signal
(Increase the concentration of the second messenger)
What is cAMP’s response to an extracellular signal?
Rapid rise of cAMP
