14B Assignment Flashcards

1
Q

If a mitochondrion wears out and can no longer maintain a proton gradient, it will also stop:

Fusion
Fission

A

Fusion

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2
Q

For electron carriers that are essential for many redox reactions in mitochondrial metabolism, what metal ion is necessary to support proper function of these electron carriers?

calcium
iron
potassium
magnesium

A

iron

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3
Q

Does succinate dehydrogenase, a component of the citric acid cycle, transfer electrons to the electron transport chain via action of NADH dehydrogenase (a.k.a. respiratory complex I)?

no
yes

A

no

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4
Q

Generally, for generation of the proton gradient across the inner mitochondrial membrane that is responsible for proton motive force is dependent on movement of protons from the _________ to the _______.

matrix; intermembrane space

intermembrane space; matrix

A

matrix; intermembrane space

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5
Q

When cytochrome c oxidase catalyzes the production of two water molecules, that requires incorporation of _______ into the water produced.

two protons and two electrons

four protons and four electrons

A

four protons and four electrons

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6
Q

Given the site of oxidation of NADH by NADH dehydrogenase, where is cytochrome c located?

cristae spaces

matrix

cytosol

A

cristae spaces

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7
Q

Which would be likely to interact with hydronium (H3O+)?

See figure legend for details of the other choice. Here, yes, partial negative charges on the hdroxyl groups of serine or threonine side chains

See figure legend for details of the other choice. Here, yes, negatively charged side chains of glutamate or aspartate

both

A

both

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8
Q

In a model of proton pumping by NADH dehydrogenase and cytochrome c oxidase. The proton is shown binding to the high-affinity state of the protein from the ________.

matrix side
cristae space

A

matrix side

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9
Q

The cristae spaces are parts of the ______ formed by the folding of the inner membrane.

intermembrane space
cytosol
matrix

A

intermembrane space

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10
Q

The NADH dehydrogenase pumps up to four H+ per electron, the cytochrome c reductase complex pumps two, whereas the cytochrome c oxidase complex pumps one per electron. So, how many protons are pumped after delivery of two electrons from NADH via NADH dehydrogenase.

seven
14
14 or fewer
seven or fewer

A

14 or fewer

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11
Q

The NADH dehydrogenase pumps up to four H+ per electron, the cytochrome c reductase complex pumps two, whereas the cytochrome c oxidase complex pumps one per electron. How many protons are pumped for two electrons from activity of succinate dehydrogenase, entering at ubiquinone and bypassing NADH dehydrogenase?

three
six
seven
14

A

six

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