16E Assignment Flashcards
Interphase animal cells generally have a major MTOC near the _____ of the cell.
Center
Periphery
Center
In animal centrosomes, how are the centrioles connected to the gamma-TuRCs?
directly attached
via plectin
indirectly through pericentriolar material
no connection even indirectly, totally isolated
via MT binding proteins
indirectly through pericentriolar material
The centering activity of MTs is dependent on a living cell that can generate ATP.
True
False
False
Centrioles are found in all eukaryotic cells.
True
False
False
Kinesins are remarkable in that _____ identical, but intertwined, allosteric motor domains work in such a highly coordinated way to move on a MT.
2
4
8
80
800
2
(i) In the kinesin cycle of motor activity, _____ binding leads to tight MT binding.
ATP
ADP
Leading head
Pi
neck linker
ATP
(ii) In the kinesin cycle of motor activity, ATP binding rigidifies the _____ in a forward-pointing direction.
ATP
ADP
Leading head
Pi
neck linker
neck linker
(iii) In the kinesin cycle of motor activity, ______ release is required to throw the lagging head forward.
ATP
ADP
Leading head
Pi
neck linker
Pi
(iv) In the kinesin cycle of motor activity, as it flies forward the previously lagging head is _____ bound.
ATP
ADP
Leading head
Pi
neck linker
ADP
(v) In the kinesin cycle of motor activity, the _____ is loosely bound to MTs.
ATP
ADP
Leading head
Pi
neck linker
Leading head
As a generalization, kinesins and myosin are _____ end-directed, while dyneins are _____ end-directed.
+, also +
-, also -
-, +
+, -
immobile, immobile
+, -
As an iron-clad rule, kinesins and dynein are _____ specific motors, while myosins are _____ specific motors.
MT, actin
MT, IF
actin, MT
IF, MT
actin, IF
MT, actin
Cytoplasmic dyneins can latch onto large vesicle cargos with the help of _____ to connect with the membrane.
Actin
Arp3
Arp2
Arp1
Arp0
Arp1
