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Pharmacology LECOM SH > Ch. 10 > Flashcards

Ch. 10 Flashcards

1
Q

inhib. Cat. Synthesis

A

a-methyltyrosine

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2
Q

phochromocytoma associated HTN

A

a-methyltyrosine

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3
Q

inhib. Cat. Storage (temp. increase cat in synapse, but long term pool depleted)

A

reserpine, Guanathedine, Guanadrel, Amphetamine, Methlyphenidate, Pseudoephedrine

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4
Q

HTN (Cat. Storage Inhib)

A

Reserpine (inhib. VMAT, w/ psychotic depression)

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5
Q

HTN (Cat. Storage Inhib)

A

Guanathedine,Guanadrel (displace NE in transmitter vesicle)

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6
Q

ADHD,Narcolepsy

A

Amphetamine, methylphenidate (displace cat., weakly inhibit MAO, block cat from reuptake by NET & DAT)

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7
Q

allergic rhinitis,nasal congestion

A

Pseudoephedrine

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8
Q

inhib. Cat. Reuptake

A

Cocaine, imipramine, amitriptyline

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9
Q

MAOI-causing increase in cat, by blocking cat. Degredation

A

Phenelzine, Iproniazid, Clorgyline, Tranylcypromine, Brofaomine, Moclobemide, Befloxatone, Selegiline (Can cause serotonin syndrome & hypertensive crisis)

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10
Q

a1- agonist -increase periph vasc. Resistance

A

methoxamine, Phenylephrine, Oxymetazoline, Tetrahydrozoline

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11
Q

hypotension, shock

A

Methoxamine

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12
Q

opthalmic hyperemia,nasal congestion,hypotension

A

Phenylephrine, Oxymetazoline, Tetrahydrozoline

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13
Q

a2-agonist- inhbit sympathetics from CNS

A

Clonidine, Dexmedetomidine, Guanabenz, Guanfacine, Methyldopa

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14
Q

HTN,opoid withdrawal, CA pain,ICU sedation,Preg. HTN

A

Clonidine, Dexmedetomidine, Guanabenz, Guanfacine, Methyldopa (choice for preg. w/ HTN)

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15
Q

B-agonist -bronchodilation

A

Metaproterenol, Isoproterenol, Salmeterol, Terbutaline, Albuterol, Dobutamine

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16
Q

a-antagonist -block cat. Causing vasodilation, decr. BP, dec. periph resistance

A

Phenoxybenzamine, Phentolamine, Prazosin, Terazosin, Doxazosin, Tamsulosin, Yohimbine

17
Q

phochromocytoma associated HTN ,sweating

A

Phenoxybenzamine, Phentolamine- alpha 1,2- Used preoperatively

18
Q

HTN, BPH

A

Prazosin, Terazosin, Doxazosin- alpha 1- AR: postural Hypotension

19
Q

BPH

A

Tamsulosin- alpha 1a (more specific to GU tract)

20
Q

Organic,psychogenic impotence

A

Yohimbine- alpha 2a

21
Q

B-antagonist -block B-receptors

A

Block B-adronergic receptors

22
Q

HTN,angina,heart failure,phochromocytoma,Glaucoma

A

Propranolol, Nadolol, Timolol, Penbutolol, Levobunolol, Carteolol- B1,2 blockers- Propranolol is lipophilic= cross CNS= high sedation

23
Q

HTN, angina (a1, B1,2 blockers)

A

Labetalol, Carvedilol- a1, B1,2

24
Q

HTN, angina (Partial agonist at B1,2)

A

Pindolol, Acebutolol

25
Q

HTN, angina,heart failure,Thyroid storm (B1 blocker)

A

Esmolol (thyroid storm=very short half life), Metoprolol, Atenolol, Betaxolol, Nebivolol

Pharmacology LECOM SH (24 decks)

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