Cell cycle Flashcards
what is the spindle made from ?
microtubules
what is the order of mitosis?
Interphase (G1, S, G2) - prophase - meta phase - anaphase - telophase - (cytokinesis)
Describe the chromosomes in interphase
uncoiled and invisible
Describe G1
Longest stage of cell cycle, highly metabolically active, cell grows, chromosomes consist of one chromatid
Describe S
DNA replicates so chromosomes contain 2 identical sister chromatids
Describe G2
Further intense cellular activity, mitochondrion divide, ATP stores increase
Describe prophase
Chromosomes coil (spiralisation) making them visible, spindle forms, nucleolus disappears
Describe metaphase
Chromosomes move to the equator of spindle and attach to spindle fibres by their centromeres, lined up
Describe anaphase
Centromere splits, spindle fibres pull chromatids by centromere to opposite poles
Chromosomes now only 1 chromatid, so cell is 4n
Describe telophase
Chromosomes uncoil and become invisible, nuclear envelopes from around two groups of chromosomes, new nucleoli forms, spindle breaks down, (centrioles replicate in animals)
Describe cytokinesis
Cell divides into 2 identical diploid daughter cells (2n)
Describe animal cytokinesis
micro tubules constrict the cell around the equator, pinching the cell into two
Describe plant cytokinesis
cell plate forms along equator, from which cell wall forms, diving the cell into two
what are stem cells ?
unspecialized cells that develop to become specialized cells by the process of differentiation
what is the difference between embryo stem cells and adult stem cells ?
embryo stem cells are pluripotent, adult stem cells are multipotent
where are most adult stem cells in humans ?
bone marrow - to produce erythrocytes and neutrophils