Cell Cycle Flashcards
1
Q
what is cell proliferation ?
A
- cell grows + divides to produce 2 daughter cells
2
Q
what are the three main types of cells (growth) ?
A
- labile cells
- stable cells
- permanent cells
3
Q
what are labile cells + example ?
A
- constantly dividing
- epithelial cells
4
Q
what are stable cells + example ?
A
- low rate of division normally but can rapidly divide in response to injury or stimuli.
- eg. hepatocytes
5
Q
what are permanent cells ?
A
- permanently differentiated so unable to divide
- eg. neurons
6
Q
what is an example of illness with decreased proliferation and increased cell death ?
A
- chronic wound
7
Q
what is an example of illness with increased proliferation and decreased cell death ?
A
- cancer
8
Q
what are the 3 stages of the cell cycle ?
A
- Interphase
- Mitosis (nuclear division)
- Cytokinesis (cytoplasm division)
9
Q
what are the stages of interphase ?
A
- G1 phase (gap 1 )
- S Phase
- G2 phase
10
Q
what happens during the G1 phase ?
A
- cell grows before DNA synthesis
- synthesizes proteins + organelles
11
Q
what happens during the S Phase ?
A
- DNA replication
12
Q
what happens during the G2 Phase ?
A
- after DNA synthesis, lasts until cell division
13
Q
what is G0 phase ?
A
- cells can enter G0 from G1 if conditions aren’t favourable
- resting phase
- do not divide
14
Q
what cells are permanently in the G0 Phase ?
A
- nerve cells
15
Q
what are the 5 Phases of Mitosis ?
A
- prophase
- prometaphase
- metaphase
- anaphase
- telophase