CD antigens

Question 1

Adhesion molecule. Expressed on T cells, thymocytes, and natural killer cells.

Answer 1

CD2

Question 2

Expressed on T cells and thymocytes. Associated with the T cell antigen receptor (TCR).

Answer 2

CD3

Question 3

Expressed on helper (Th1 and Th2) T cells (about 60% of peripheral T cells). Co-receptor for MHC II.

Answer 3

CD4

Question 4

Expressed on a subset of B cells, thymocytes, and T cells.

Answer 4

CD5

Question 5

Expressed on cytotoxic (killer) (Tc) and suppressor (Ts) T cells. Co-receptor for MHC I.

Answer 5

CD8

Question 6

Expressed on B cells

Answer 6

CD19, CD20, CD21, CD22

Question 7

Low affinity receptor for IgE. Expressed on mature B cells, macrophages, eosinophils, and some other cells.

Answer 7

CD23

Question 8

IL-2 receptor (IL-2R) alpha chain. Expressed on T cells, B cells, and monocytes.

Answer 8

CD25

Question 9

Receptor for co-stimulatory signal, binds B7.1 and B7.2. Expressed on B cells and subsets of T cells.

Answer 9

CD28

Question 10

Receptor for co-stimulatory signal, binds CD40 ligand (CD40-L). Expressed on B cells, monocytes, and dendritic cells.

Answer 10

CD40

Question 11

Ligand for CD40. Expressed on activated CD4 T cells.

Answer 11

CD40-L

Question 12

Mediates adhesion of leukocytes.

Answer 12

CD44

Question 13

Has multiple isoforms resulting from alternative splicing (CD45RO, CD45RA, CD45RB). Another popular name for this phosphotyrosine phosphatase enzyme is leukocyte common antigen (LCA). Amplifies the signaling through antigen receptor of B and T cells.

Answer 13

CD45

Question 14

Fas. Induces apoptosis.

Answer 14

CD95