CCDM: TOPIC SMALLPOX

Question 1

The last naturally acquired case of smallpox in the world occurred in what year and country?

Answer 1

Oct 1977 in Somalia

Question 2

When was global eradication certified and by what group?

Answer 2

1979 by WHO and sanctioned by World Health Assembly (WHA) in May 1980.

Question 3

Where are all known variola virus stocks held under security?

Answer 3

CDC, Atlanta GA, USA and the Russian Federation Novosibirsk Region.

Question 4

Smallpox signs and symptoms are?

Answer 4

high fever (40°C/104°F), malaise, headache, prostration, severe backache and occasional abdominal pain and vomiting

Question 5

What are two types of smallpox?

Answer 5

variola minor (alastrim) and variola major

Question 6

What is variola minor case fatality rate?

Answer 6

less than 1%

Question 7

What is variola major case fatality rate?

Answer 7

Among unvaccinated populations of 20-50% or more with death occurring on fifth and seventh day.

Question 8

Infectious agent of Smallpox

Answer 8

Variola virus, a species of Orthopoxvirus

Question 9

Mode of transmission for Smallpox

Answer 9

Respiratory tract (droplet spread) or skin inoculation

Question 10

Incubation period

Answer 10

7-19 Days total; 10-14 for onset of illness and 2-4 day more to onset of rash.