Carlson et al (1999) Flashcards
aim
to conduct a review of current research to study the relationship between neurotransmitters other than dopamine that could be implicated in causing sz
procedure
reviewed various research findings investigating neurochemical levels in patients diagnosed w sz and drugs known to induce symptoms
findings
as well as dopamine research showed that noradrenaline, serotonin, acetylcholine, glutamate and gaba as likely neurotransmitters to relate to sz. low glutamate levels related to sz. Clozapine most effective for d+s. positive symptoms resulted form glutamate failure in the cerebral cortex. negative symptoms resulted from glutamate failure in the basal ganglia.
conclusion
further research into glutamate deficiency needs to happen. Schizophrenia may’ve different types that can be caused by abnormal levels of different neurotransmitters.
:) meta analysis
a meta analysis allowed Carlson to increase the sample size as well as improving the statistical power of the findings. T/F a larger sample size increases the population validity of the study
:) practical applications
the knowledge that different neurotransmitters other than dopamine can relate to sz can her to improve future research + treatments T/F carillons findings have practical applications to society .
:( informed consent- secondary data
ethical guideline of informed consent was breached since Carlson used secondary data, he did not have the consent of the people within the data. T/F ethical guideline of informed consent was breached