Cardiovascular System Pt.3 - Excitability of the Heart & Blood Vessels Flashcards

1
Q

How are the cardiac muscle able to cause the heart to contract?

A

Self-excitable cells; initiate signal telling heart to contract

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2
Q

What is the pathway of the signal propagated to cause the heart to contract

A
  1. Sinoatrial Node
  2. Atrioventricular Node
  3. Atrioventricular Bundle (Bundle of His)
  4. Right and left bundle branches
  5. Purkinje Fibres

Note: These places are where there are clumps of cardiac muscle

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3
Q

How does the Sinoatrial Node work?

A

Right near the top of the atria; “pacemaker of the heart” which makes it this modified cardiac muscle cell that generates own electrical signals causing contractions of the cardiac muscle atria

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4
Q

What is unique about the SA node?

A
  • Generates it’s own signal
  • Autonomic Nervous System can speed up/slow down that signal
  • Parasympathetic signal slows RHR from 100bpm ==> 70bpm
  • Sends signal to both atria to make them contract in unison

Vagal tone: Slows the RHR from 100 to 70

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5
Q

What is the AV node?

A

Located on the floor of the right atria; picks up signal from SA node and transfers it down to the AV Bundle

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6
Q

What is the AV bundle?

A

Modified cardiac muscle cells that carry the signal and splits into the right and left bundle branches

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7
Q

What is the right and left bundle branches?

A

Bundle branches that continue to carry that electrical signal; split into these right and left and run along the ventricle called purkinje fibres

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8
Q

What are the purkinje fibres?

A
  • Responsible for delivering signal throughout ventricles
  • Found in the “interventricular septum” of the ventricles
  • Coordinated contraction of both ventricles and papilary muscle (Holds AV valve shut when ventricles contract)
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9
Q

What are the three classes of arteries and how are they different?

A
  1. Elastic artery
  2. Muscular artery
  3. Arteriole
  • Based on elasticity and size
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10
Q

When blood leaves the heart where does it go?

A

Elastic arteries; very big and elastic arteries that need to take on the massive amount of pressure blood being pumped through them

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11
Q

As blood moves through the body the arteries branch off and become smaller. After the elastic artery where does blood go through?

A
  • Muscular arteries; smaller and less elastic because no high amounts of pressure to withstand since it is all branched out
  • After muscular arteries they go to arterioles; much smaller than muscular which then go to capillaries
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12
Q

What does the blood from the artery (arteriole specifically) difuse into?

A

Capillaries; oxygen diffuses into the capillaries and the arteriole blood picks up CO2

Capillaries have single cell wall

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13
Q

Where does blood go after diffusion occurs with the capillaries

A

Into the veins; specifically the venule which is the smallest type of veins

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14
Q

After the venule where does the blood go?

A

Medium-sized vein

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15
Q

After the medium sized-vein where does blood go?

A

Large veins and into the heart

Inferior vena cava is a large vein

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16
Q

How many layers of blood vessels are there and what are they?

A

3 layers

  1. Tunica Interna
  2. Tunica media
  3. Tunica Externa
17
Q

What is the Tunica interna? What is it made of?

A
  • Innermost layer of blood vessels made of simple squamous epithelial cells
  • Within arteries and veins & capillaries
18
Q

How many layers does the capillary have and what does it contain?

A
  • One layer; Tunica Interna
  • Simple squamous cells for gas exchange
19
Q

What layer is superficial to the Tunica Interna but deep to the Tunica Externa

A

Tunica Media; muscular layer
* Thick on arteriole (Thickest layer of wall) side but not on venous side
* Made of smooth muscle cells

20
Q

Why must the Tunica Media have a thick muscular layer?

A

So the arteries can control blood distribution
* If eating and trying to digest but a tiger runs in, your tunica media gets a sympathetic signal to constrict in the GI Tract and the blood goes to the leg muscles to run away

21
Q

What is the Tunica Externa

A

Outermost layer only in arteries and veins
* Made mostly of aerioler connective tissue

22
Q

What is unique to the Tunica Externa and the veins?

A

Thickest wall for veins

23
Q

Purpose of Tunica Externa

A

More structural; anchor blood vessels to nearby structure

24
Q

What is the purpose of valves in the venous system?

A

To help return blood to the heart because blood moves up against gravity plus not as much muscle on veins to push.

25
Q

What ways does blood go through the veins to the heart?

A
  1. Moving of blood through the valves and closing them once it moves along
  2. Massaging action of muscles - Musculovenous Pump
    * When muscles near the vein contract it pushes on vein to push blood up

Musculovenous Pump important in lower limbs and diaphragm