Cardiovascular Dysfunction Flashcards

1
Q

What are some signs of cardiac dysfunction during H&P?

A

poor feeding

rapid breathing

difficulty keeping up with friends

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2
Q

What aspects of the mother’s health history could cause cardiac dysfunction in the infant?

A

diabetes

lupus

phenytoin

alcohol

drugs

infections (rubella)

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3
Q

how does low birth weight affect cardiac function?

A

increased risk of congenital anomalies

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4
Q

how does high birth weight affect cardiac function?

A

increased risk of heart disease

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5
Q

what family history might increase risk of cardiac dysfunction?

A

parents or siblings with heart defects

marfan syndrome

fetal loss

SIDS

Down syndrome

turner syndrome

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6
Q

what nutritional signs might indicate cardiac dysfunction?

A

failure to thrive

poor weight gain

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7
Q

what skin colours (2) might indicate cardiac dysfunction?

A

cyanosis = congenital heart defect

pallor = poor perfusion

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8
Q

what does an abnormal chest shape indicate?

A

enlarged heart

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9
Q

what are some respiratory signs of cardiac dysfunction?

A

tachypnea

dyspnea

expiratory grunt

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10
Q

clubbing is associated with ________

A

cyanosis

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11
Q

upon inspection, what signs might indicate cardiac dysfunction?

A

failure to thrive
poor weight gain
cyanosis
pallor
abnormal chest shape
tachypnea
dyspnea
expiratory grunt
visible neck vein pulsations
clubbing

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12
Q

upon palpation, what signs might indicate cardiac dysfunction?

A

thrills (chest)

hepatomegaly

splenomegaly

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13
Q

upon auscultation, what signs might indicate cardiac dysfunction?

A

tachycardia

bradycardia

irregular rhythms

murmurs

extra sounds

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14
Q

What are the diagnostic tests for cardiac dysfunction?

A

chest x-ray

ECG

echocardiography

cardiac catheterization

exercise stress test

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15
Q

What does a chest x-ray show?

A

heart size

blood flow

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16
Q

What does an ECG show?

A

electrical activity

detect dysrhythmias

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17
Q

What does na echocardiogram show?

A

cardiac structures

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18
Q

what does cardiac catheterization measure?

A

pressure and oxygen in heart chambers

cardiac structures

blood flow

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19
Q

what does an exercise stress test measure?

A

HR, BP, ECG and O2 consumption at rest and during exercise

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20
Q

what are the 2 types of cardiac defects?

A
  1. congenital heart disease
  2. acquired
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21
Q

what is congenital heart disease?

A

anatomical, abnormal function

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22
Q

what is the cause of congenital heart disease?

A

unknown

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23
Q

what is congenital heart disease associated with?

A

chromosomal abnormalities

Trisomy 21, 13, and 18

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24
Q

what is the most common anomaly with congenital heart disease?

A

ventricular septal defect

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25
what is a ventricular septal defect?
hole between right and left ventricles
26
what is the foramen Ovale? when does it close?
shunts blood from RA to LA closes when LA pressure exceeds RA pressure
27
what is the ductus arteriosus? when does it close?
shunts blood from pulmonary artery to aorta bypasses lungs closes when baby takes first breath blood oxygen concentration increases
28
what happens if the FO and DA don't close after birth?
congenital heart defects
29
what causes cyanosis (CHD)?
change in pressure right to left shunt deoxygenated blood bypasses lungs decreased oxygen delivery
30
acyanosis (CHD)
presence of CHD but O2 delivery unaffected no cyanosis
31
what are the 4 types of congenital heart defects? are they cyanotic or acyanotic?
1. increased pulmonary blood flow (acyanotic) 2. decreased pulmonary blood flow (cyanotic) 3. obstruction (acyanotic) 4. mixed blood flow (cyanotic)
32
increased pulmonary blood flow congenital heart defect
opening between atria blood flows L to R increased blood volume on R side increased pulmonary blood flow decreased systemic blood flow
33
what are the signs and symptoms of increased pulmonary blood flow congenital heart defect?
asymptomatic heart failure murmurs atrial dysrhythmias
34
what are some examples of increased pulmonary blood flow congenital heart defect?
atrial septal defect ventricular septal defect patent ductus arteriosus
35
decreased pulmonary blood flow congenital heart defect
pulmonary blood flow obstruction + anatomical defect blood has difficulty leaving heart through pulmonary artery blood shunts right --> left bypassing lungs deoxygenated blood enters systemic circulation
36
what are the signs and symptoms of decreased pulmonary blood flow congenital heart defect?
hypoxemia cyanosis
37
what are some examples of decreased pulmonary blood flow congenital heart defect?
tetralogy of fallot tricuspid atresia
38
what is tetralogy of fallot?
4 structural defects 1. ventricular septal defect 2. pulmonic stenosis 3. overriding aorta 4. RV hypertrophy
39
what is tricuspid atresia?
tricuspid valve fails to develop
40
obstruction of blood flow congenital heart defect
blood exiting heart meets stenosis pressure before obstruction increases (in ventricle) pressure after obstruction decreases occurs near valve
41
what are the signs and symptoms of obstruction of blood flow congenital heart defect?
decreased CO heart failure hypoxemia asymptomatic
42
what are some examples of obstruction of blood flow congenital heart defect?
coarctation of aorta (narrowing of aortic arch) aortic stenosis pulmonic stenosis
43
mixed blood flow congenital heart defect
oxygenated and unoxygenated blood mix causes desaturation of systemic blood flow decreased CO
44
what are the signs and symptoms of mixed blood flow congenital heart defect?
cyanosis heart failure
45
what are some examples of mixed blood flow congenital heart defects?
transposition of great arteries total anomalous pulmonary venous connection truncus arteriosus hypo plastic left heart syndrome
46
what is transposition of great arteries?
arteries switch pulmonary artery leaves LV aorta leaves RV
47
what is total anomalous pulmonary venous connection?
pulmonary veins connect to R side of heart instead of LA
48
what is truncus arteriosus?
only one artery leaves the heart instead of the pulmonary artery and aorta
49
what is hypo plastic left heart syndrome?
underdeveloped L side of heart
50
what are the 2 consequences of congenital heart defects?
1. heart failure 2. hypoxemia
51
what is heart failure?
inability of heart to pump adequate blood into systemic circulation
52
what is R sided HF?
RV fails to pump blood into pulmonary artery increased pressure in RV and systemic circulation
53
what are some signs and symptoms of R sided HF?
hepatosplenomegaly edema
54
what is L sided HF?
failure of LV to pump blood into systemic circulation increased pressure in LA and pulmonary veins
55
what are some signs and symptoms of L sided HF?
pulmonary edema crackles
56
what are the consequences of HF?
myocardial damage decreased CO decreased kidney perfusion
57
how do the kidneys respond in HF?
decreased kidney perfusion kidneys think fluid volume is low reabsorb more sodium and water fluid overload
58
what are the 4 goals of treatment for HF?
1. improve cardiac function 2. decrease fluid 3. improve oxygenation 4. decrease cardiac demand
59
what 3 medications can be used in HF to improve cardiac function?
1. digitalis (digoxin) 2. ACE inhibitors 3. beta blockers
60
what are the effects of digitalis (digoxin)?
increases contractility without increasing HR increases CO decreases heart size
61
do not administer digoxin if HR is < _____________
< 90 bpm
62
what are the effects of ACE inhibitors?
vasodilation decreased aldosterone decreased sodium and water reabsorption
63
what are the adverse effects of ACE inhibitors?
hypotension cough renal dysfunction
64
what are the adverse effects of beta blockers?
hypotension dizziness
65
what medication is used to decrease fluid in HF?
diuretics - thiazide - furosemide
66
what are the interventions for decreasing fluid in HF?
diuretics fluid and sodium restriction monitor intake and output prevent dehydration
67
what are the interventions for decreasing cardiac demand in HF?
decrease WOB encourage sleep schedule feeds around sleep - prevent hunger maintain body temp
68
what is hypoxemia?
decreased arterial oxygen saturation
69
what are the 2 clinical manifestations of hypoxemia?
hypoxia cyanosis
70
what is hypoxia?
decreased tissue oxygenation
71
what are the 2 physiological changes in response to chronic hypoxemia?
polycythemia clubbing
72
what is polycythemia?
increased RBCs to compensate for hypoxemia increased O2 carrying capacity
73
what is the risk associated with polycythemia?
increased blood viscosity increased risk of clotting
74
mild hypoxemia is ____________
asymptomatic
75
what are some signs of severe hypoxemia?
fatigue with feeding poor weight gain tachypnea dyspnea
76
what are some complications of hypoxemia?
mostly neurological - CVA - stroke - abscesses - developmental delays
77
what is the goal of hypoxemia diagnosis?
distinguish between cardiac or pulmonary cause PaO2 > 100 mmHg = lung disease PaO2 < 100 mmHg = cardiac disease
78
what is the treatment for hypoxemia?
IV prostaglandin E
79
what are the effects of prostaglandin E?
vasodilation
80
what are hypercyanotic spells?
severe cyanotic episodes
81
what causes hypercyanotic spells? what are some triggers?
spontaneous OR decreased SVR triggers - feeding - crying - defecation - stress
82
hypercyanotic spells are associated with ___________
tetralogy of fallot
83
what are the treatments for hypercyanotic spells?
knee to chest position oxygen therapy morphine IV fluid replacement
84
what does the knee to chest position do?
increases systemic vascular resistance
85
what is acquired cardiac defect?
caused by a disease process
86
what are some causes of acquired cardiac defects?
infection autoimmune response familial tendencies medications environmental
87
what are the 2 acquired cardiac defects?
endocarditis cardiomyopathy
88
what is endocarditis?
infection of endocardium
89
what are the causes of endocarditis?
bacteremia congenital anomalies dental work invasive procedures central lines IV drug use
90
what are the common pathogens that cause endocarditis?
S. aureus streptococcus fungi
91
what are the clinical manifestations of endocarditis?
fever malaise weight loss janeway lesions osler nodes roth spots
92
what are janeway lesions?
nontender erythematous macule on palms and feet
93
janeway lesions are more common in ___________ endocarditis
acute
94
what are Osler nodes?
tender subcutaneous violet nodules on pads of fingers and toes
95
what are Roth spots?
exudative edematous hemorrhagic lesions of the retina
96
what are the treatments for endocarditis?
IV antibiotics surgery high risk: antibiotic prophylaxis
97
what is cardiomyopathy?
myocardial abnormality causing impaired cardiac muscle contraction
98
what are the causes of cardiomyopathy?
familial or genetic infection deficiencies hemochromatosis Duchenne muscular dystrophy Kawasaki disease collagen vascular disease thyroid dysfunction
99
what are the 3 types of cardiomyopathy?
1. dilated 2. hypertrophic 3. restrictive
100
what is dilated cardiomyopathy?
decreased contractility
101
what is the most common form of cardiomyopathy in children?
dilated
102
what are the symptoms of dilated cardiomyopathy?
HF symptoms
103
what is hypertrophic cardiomyopathy?
LV hypertrophy causes abnormal filling
104
what is restrictive cardiomyopathy?
decreased ventricular filling
105
how is cardiomyopathy diagnosed?
ECG exercise stress test MRI genetic testing
106
what is the goal of treatment for cardiomyopathy?
correct underlying cause
107
what is the first line of treatment for cardiomyopathy?
beta blocckers
108
what are the other treatment options for cardiomyopathy?
diuretics Ca2+ channel blockers implantable cardioverter or defib anticoagulants heart transplant (if severe)
109
what medication should NOT be given for cardiomyopathy?
digoxin
110
what are the 3 main vascular dysfunctions?
hypertension Kawasaki disease shock
111
what is primary hypertension?
no identifiable cause
112
what is secondary hypertension?
identifiable cause
113
what are the possible causes of HTN?
renal disease CVD endocrine disorder neurological disorder
114
what is Kawasaki Disease?
mucocutaneous lymph node syndrome acute systemic vasculitis of medium sized arteries especially coronary arteries
115
what is the cause of Kawasaki disease?
unknown
116
Kawasaki disease most seriously affects ____________
infants < 1 year
117
what is the main clinical manifestation of Kawasaki?
inflammation of medium sized arteries
118
what are the 3 phases of Kawasaki disease?
1. acute 2. subacute 3. convalescent
119
what is the acute phase of Kawasaki disease?
high fever unresponsive to antibiotics and antipyretics
120
what is the subacute phase of Kawasaki disease?
fever resolves high risk for aneurysms lasts until clinical signs resolve
121
what is the convalescence phase of Kawasaki disease?
clinical signs resolved abnormal lab values lasts until temp and lab values are normal
122
how is Kawasaki disease diagnosed?
no tests based on clinical findings echocardiogram
123
what are 2 good indicators of possible Kawasaki disease?
prolonged fever unresponsive to antibiotics
124
the diagnostic criteria for Kawasaki disease should be used as a ____________
guideline
125
what is the diagnostic criteria for Kawasaki disease?
fever for 5+ days and 4/5 criteria 1. bulbar conjunctival injection 2. oral mucous membrane changes - injected or fissured lips - injected pharynx - strawberry tongue 3. peripheral extremity changes - edema - erythema 4. polymorphous rash 5. cervical lymphadenopathy
126
when should treatment for Kawasaki disease start?
within 10 days of symptom onset
127
how is Kawasaki disease treated?
IV immunoglobulin aspirin salicylate anticoagulants
128
what is shock?
inadequate perfusion leads to organ failure
129
what are the 3 types of shock?
1. hypovolemic 2. distributive 3. cardiogenic
130
what are the causes of hypovolemic shock?
burns trauma hemorrhagic diarrhea vomiting
131
what are the causes of distributive shock?
anaphylaxis sepsis myocardial depression
132
what are the causes of cardiogenic shock?
heart failure dysrhythmias
133
what are the 3 stages of shock?
1. compensated 2. decompensated 3. irreversible
134
what is compensated shock?
vital organ function maintained by compensatory mechanisms
135
what is decompensated shock?
decreased cardiovascular function
136
what is irreversible shock?
vital organ damage
137
what are some complications of shock?
cerebral edema hemorrhage renal ischemia resp distress GI bleeding hypoglycemia hypoclacemia
138
what are the 3 treatments for shock?
1. ventilation 2. fluids 3. improve cardiac function
139
how do we improve ventilation during shock?
tracheal intubation + positive pressure supplemental oxygen
140
what fluids should be administered for shock?
crystalloids colloids