Capter 7: Muscular System (Muscle Notes) Flashcards
Functions of skeletal muscle
Produce movement Maintain posture and body position support soft tissues guard entrance/ exits maintain body temperature
Gross anatomy of a Muscle
3 layers of connective tissue - Epimysium -perimysium - Endomysium All layers come together to form tendon
Epimysium
separates muscle organ from surrounding tissues and organs
Perimysium
divides bundles of muscle fibers into fascicles
- contains blood vessels and nerves that supply fasicles
Endomysium
surrounds muscle fibers and ties them together
tendons are what type of tissue
connective
Microanatomy
cell membrane= sarcolemma
cytoplasm= sarcoplasm
transverse tubules- network of tunnels that coordinate contraction
myofibrils
- 1-2 um diameter/ run length of muscle
- 000’s contained in 1 muscle fiber
- made up of thick (myosin) and thin (actin) filaments
sarcoplasmic reticulum
- surrounds each myofibril
- contains calcium ions, used for contraction
- release of calcium initiates muscle contraction
Sarcomeres
- smallest functional unit of the muscle fiber
- produces striated appearance
- thick and thin filaments line up next to each other
- neither filament spans the entire sarcomere
Thick and thin filaments
-actin molecules have an active site that interacts with myosin
=tropomyosin covers these sites when “resting”
- Myosin has a globular head and tail
- Calcium is the key that unlocks active sites and begins a contraction
= bond to tropomyosin, causes change in shape
how do muscles control contraction?
Control of Muscle Contractions
- neuromuscular junctions link nervous and muscular systems
- release of acetylcholine triggers release of Calcium ions
sacolemma
cell membrane
sarcoplasm
cytoplasm
transverse tubules
network of tunnels that coordinate contraction
resting sarcomere
the unit of the muscle that contracts to allow movement
once calcium leaves, it causes
shape change, blocking actin from bonding with myosin
tropomyosin acts as
the lid to the cookie jar
rigor mortis
-circulation ceases upon death
- run out of ATP which leaves SR unable to remove Calcium
- What happens?
= causes a sustained contraction bc no ATP available to detach cross bridges
= lasts for 15-25 hours (enzymes break down everything)
Muscle Mechanics
-muscles pull, causing tension
=must overcome resistance
-cannot push away from an object (compression)
= because muscle cells can only contract, sarcomeres can not widen
twitch
single stimulation sequence of a fiber
muscle fiber
twitch 3 phases: - latent: calcium removed -contraction: sliding filament - relaxation: actively takes out calcium from the SR
Tetanus
- summation
- incomplete tetanus
- complete tetanus
Summation
addition of one twitch to another
incomplete tetanus
produces almost peak tension
complete tetanus
occurs when relaxation phase completely eliminated
tetanus
lock jaw
- caused by a bacterium (clostridium tetani)
- thrives in low oxygen, like deep tissue
- releases toxin affecting motor neurons, yielding contraction of muscles
- 40-60% mortality rate
- no after effect, after 2-4 weeks
motor units, muscle fibers are controlled by what?
a single motor neuron
- size of unit determines how fine level of control is
- fewer fibers= greater control
what occurs when all motor units of a muscle are activated?
peak tension
sustained contractions
motor units will activate on rotating basis
the resting tension in muscle causes
no movement is caused
- stabilizes position of muscles and bones
atrophy
regular stimulation by a motor neuron is NOT achieved- becomes weak ex: broken arm or leg
types of contractions
isometric
isotonic
isometric
no joint movement (plank, wall squats, static lunges, yoga)
- muscle remains same in length
- tension never exceeds resistance
ex: pushing against a wall/ holding
isotonic
joint moves
- muscle holds same tension
- contracts up to a point where resistance is over come (moves)
ex: lifting an object, walking, running
where does each muscle begin?
at an origin (stationary)
where does each muscle end?
at an insertion (moves)
What do muscles produce?
a specific action, like flexion or extension