Cancer III Lecture Flashcards

1
Q

paraneoplastic syndromes

A

neoplasm itself elaborating a hormone

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2
Q

hypercalcemia

A

with squamous cell carcinoma of lung

PTHRP

paraneoplastic

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3
Q

cushings

A

small cell carcinoma of lung

ACTH

paraneoplastic

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4
Q

NBTE

A

nonbacterial thrombotic endocarditis

hypercoagulability
-mucinous adenocarcinomas

paraneoplastic

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5
Q

leukemia and lymphoma diagnosis

A

flow cytometry

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6
Q

molecular diagnosis

A

diagnosis and prognosis

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7
Q

pap smear

A

should get transition zone

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8
Q

multiple myeloma

A

IgG-kappa

in elderly

neoplasia of plasma cells

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9
Q

tumor markers

A

not definitive diagnosis of cancer

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10
Q

AFP

A

oncofetal

hepatocellular carcinoma
germ cell tumors (yolk sac)

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11
Q

CEA

A

oncofetal

addenocarcinoma

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12
Q

CA-125

A

recurrent check in ovarian carcinoma

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13
Q

beta-hCG

A

from syncytiotrophoblasts

male - choriocarcinoma

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14
Q

CA 19-9

A

pancreatic carcinoma

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15
Q

BRCA1, BRCA2

A

associated with predisposition to breast cancers

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16
Q

CA 15-3

A

breast carcinoma

17
Q

CA 72-4

A

gastric carcinoma

18
Q

HER2/neu

A

breast carcinoma

19
Q

alkaline phosphatase

A

osteosarcomas

  • young have high alkaline phosphatase with bony growth phase
  • slows in late teens early twenties
20
Q

TdT and beta-2 microglobulin

A

hematologic malignancy markers

TdT - primitive B cells

21
Q

SCC

A

keratin marker

22
Q

c-myc

A

burkitt lymphoma