C9 How genes evolve Flashcards
germ line
cell lineage that gives rise to germ cells
germ cells
specialized reproductive cells that come together during fertilization
Important types of genetic change that drive evolution
mutation within gene, gene duplication, gene deletion, exon shuffling, horizontal transfer
gene duplication is a result of..
unequal crossing over
exon shuffling
new combinations of exons produce new proteins
two mechanisms of exon shuffling
unequal crossing over, transposable elements
may account for unexpected similarity between archaebacteria to bacteria and eucarya
horizontal transfer
horizontal gene transfer
DNA can be transferred from one cell to another even to that of a different species
synteny
where genes have remained in the same order on chromosomes
Why is “Eve” of African origin
analysis of highly conserved mitochondrial DNA inherited from mother shows greatest diversity among African population
make excellent markers for the absolute identification of individuals
CA sequences and SNPs
what can the fugu fish tell us about human genome?
huntington genes of both share 67 exons in the same order but fugu gene is much smaller. Introns are dispensable.
huntingtons disease is called by..
trinucleotide repeats