C9 How genes evolve Flashcards

1
Q

germ line

A

cell lineage that gives rise to germ cells

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2
Q

germ cells

A

specialized reproductive cells that come together during fertilization

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3
Q

Important types of genetic change that drive evolution

A

mutation within gene, gene duplication, gene deletion, exon shuffling, horizontal transfer

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4
Q

gene duplication is a result of..

A

unequal crossing over

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5
Q

exon shuffling

A

new combinations of exons produce new proteins

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6
Q

two mechanisms of exon shuffling

A

unequal crossing over, transposable elements

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7
Q

may account for unexpected similarity between archaebacteria to bacteria and eucarya

A

horizontal transfer

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8
Q

horizontal gene transfer

A

DNA can be transferred from one cell to another even to that of a different species

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9
Q

synteny

A

where genes have remained in the same order on chromosomes

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10
Q

Why is “Eve” of African origin

A

analysis of highly conserved mitochondrial DNA inherited from mother shows greatest diversity among African population

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11
Q

make excellent markers for the absolute identification of individuals

A

CA sequences and SNPs

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12
Q

what can the fugu fish tell us about human genome?

A

huntington genes of both share 67 exons in the same order but fugu gene is much smaller. Introns are dispensable.

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13
Q

huntingtons disease is called by..

A

trinucleotide repeats

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