C5 DNA Flashcards

1
Q

Observed that heat-killed virulent cells could transform nonvirulent cells into virulent cells

A

Griffith

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2
Q

Griffith injected ? into mice

A

S. Pneumoniae

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3
Q

Gave first evidence that DNA could serve as genetic material

A

Avery, Macleod

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4
Q

The transforming principle was developed by ?

A

Griffith

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5
Q

The nature of the transforming principle was verified by ?

A

Avery, Macleod

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6
Q

How was the experiment by Avery, Macleod conducted

A

Fractionized S-strain cells into major macromolecules. DNA was only macromolecule that transformed R-strain.

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7
Q

Hershey-chase experiment was conducted using ? virus

A

T2

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8
Q

How was Hershey-chase experiment conducted?

A

DNA of virus was fluorescently labeled with one color, and protein with another. Allowed virus to infect E. Coli. DNA only present in infected bacteria.

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9
Q

typical size of cell

A

10 um

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10
Q

typical size of nucleus

A

5-8 um

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11
Q

Does chromosome number have an effect on organism complexity?

A

no

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12
Q

the most densely packaged region of chromosomes

A

heterochromatin

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13
Q

complex of DNA and proteins is called

A

chromatin

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14
Q

DNA is initially packaged by basic proteins known as ?

A

histones

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15
Q

Each histone condenses DNA by

A

3 times

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16
Q

DNA wraps around the histone ? times

A

1.65

17
Q

This histone helps pack nucleosomes to make 30 nm fiber

A

H1

18
Q

X-activation is a result of

A

one x-chromosome being completely condensed into heterochromatin

19
Q

epigenetic control

A

DNA and/or histones can be modified to mark regions for gene expression