C5 DNA Flashcards
Observed that heat-killed virulent cells could transform nonvirulent cells into virulent cells
Griffith
Griffith injected ? into mice
S. Pneumoniae
Gave first evidence that DNA could serve as genetic material
Avery, Macleod
The transforming principle was developed by ?
Griffith
The nature of the transforming principle was verified by ?
Avery, Macleod
How was the experiment by Avery, Macleod conducted
Fractionized S-strain cells into major macromolecules. DNA was only macromolecule that transformed R-strain.
Hershey-chase experiment was conducted using ? virus
T2
How was Hershey-chase experiment conducted?
DNA of virus was fluorescently labeled with one color, and protein with another. Allowed virus to infect E. Coli. DNA only present in infected bacteria.
typical size of cell
10 um
typical size of nucleus
5-8 um
Does chromosome number have an effect on organism complexity?
no
the most densely packaged region of chromosomes
heterochromatin
complex of DNA and proteins is called
chromatin
DNA is initially packaged by basic proteins known as ?
histones
Each histone condenses DNA by
3 times
DNA wraps around the histone ? times
1.65
This histone helps pack nucleosomes to make 30 nm fiber
H1
X-activation is a result of
one x-chromosome being completely condensed into heterochromatin
epigenetic control
DNA and/or histones can be modified to mark regions for gene expression