C12 membrane transport Flashcards

1
Q

move molecules from one side of membrane to other using conformational change

A

carrier proteins

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2
Q

small pore that allows specific ions to flow by diffusion

A

channel proteins

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3
Q

Na+ is kept in high concentration (inside/outside) cell

A

outside (extracellular)

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4
Q

K+ is kept in high concentration (inside/outside) cell

A

inside (intracellular)

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5
Q

Cl- is kept in high concentration (inside/outside) cell

A

outside

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6
Q

? transport moves molecules down a concentration gradient

A

passive

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7
Q

? transport moves molecules against a concentration gradient

A

active

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8
Q

facilitated diffusion

A

passive transport specific for the molecule

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9
Q

function of insulin

A

stimulates glucose uptake in muscle and fat cells

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10
Q

Humans have ? different glucose transporters

A

5

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11
Q

insulin secretion is triggered by ?

A

increases in blood sugar

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12
Q

the cytoplasmic side of the plasma membrane us usually kept (negative/positive)

A

negative

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13
Q

the electrical gradient is derived from ?

A

the membrane potential

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14
Q

the chemical gradient is derived from ?

A

relative concentration of individual charged molecule

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15
Q

The ? pump is responsible for the membrane potential in animal cells

A

Na+,K+ ATPase

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16
Q

The Na+,K+ ATPase pumps ? Na out and ? K in

A

3,2

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17
Q

P-type pumps catalyze ?

A

autophosphorylation

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18
Q

The Na/glucose transporter is an example of (symport/antiport)

A

symport

19
Q

The Na+/H+ exhanger is an example of (symport/antiport)

A

antiport

20
Q

principal passive glucose uniport

A

GLUT 2

21
Q

insulin-regulated glucose transporter

A

glut 4

22
Q

function of Ca++ ATPases

A

maintain very low intracellular CA++ concentration

23
Q

Intracellular Ca++ can be used for ?

A

signalling

24
Q

Plants, fungi and bacteria rely primarily on gradients from ? to drive secondary transport

A

H+

25
Q

Three ways to gate ion channels

A

voltage, ligand, stress

26
Q

the acetyl choline receptor is a ? channel

A

na+

27
Q

channels spontaneously fluctuate between open and closed? t/f

A

true

28
Q

channel that establishes resting potential of -70mV

A

K+

29
Q

Depolarization of nerve cells is a result of ? (2)

A

stimulation followed by Na+ flow into cell

30
Q

Opening of Na+ channel in nerve cell occurs around this membrane potential

A

-50mV

31
Q

Na+ channel in nerve cells closes around this membrane potential?

A

+50mV

32
Q

? flow out of cell repolarizes cell

A

K+

33
Q

The Na+ channel is ? gated

A

voltage

34
Q

? cells wrap nerve axons to provide electrical insulation

A

schwann

35
Q

Is transmitted the length of the axon without additional energy input

A

action potential

36
Q

synapse

A

junction between two neurons where electrical signal is converted to neurotransmitter

37
Q

? channel triggers release of neurotransmitter

A

Ca++

38
Q

novacain function

A

blocks Na+ ion channels. prevents action potentials and therefore pain.

39
Q

nerve gas function

A

inhibitor of acetylcholine esterase. acetylcholine accumulates and keeps nerve on.

40
Q

alpha-bungarotoxin function

A

inhibitor of acetylcholine receptor. nerve cannot be stimulated by neurotransmitter

41
Q

Botox function

A

inhibits neurotransmitter release. muscles cannot be stimulated

42
Q

Prozac

A

increase serotonin levels

43
Q

provides info for how individual ion channels behave

A

patch-clamp recording

44
Q

oubain function

A

inhibiting na,k pump, inhibits glucose uptake by epithelial cells