Breast pathology

Question 1

Apocrine metaplasia

Answer 1

Never becomes malignant

Question 2

Intraductal papilloma

Answer 2

Benign
Bleeding

Question 3

Fibroadenoma

Answer 3

Mobile, round mass
benign
If over >5cm excise

Question 4

Lactational mastitis

Answer 4

Breast feeding
Staph aureus

Question 5

Periductal mastitis

Answer 5

Smokers
Vit A deficiency

Question 6

Mammary duct ectasia

Answer 6

Elderly
White DC

Question 7

Fat necrosis

Answer 7

Trauma
Calcification on mammogram

Question 8

Pagets disease of nipple

Answer 8

Strong association with breast cancer

Question 9

BRCA 1

Answer 9

Aggressive
Tripe -ve cancer
Ovarian and breast

Question 10

BRCA 2

Answer 10

Male breast - men are second class
Prostate cancer
Pancreatic cancer

Question 11

Role of MRI in breast assessment

Answer 11

Hereditary screening
Lobular invasive cancer

Question 12

Ductal CIS

Answer 12

Does not breach basement membrane
Comedo necrosis pattern

Question 13

Invasive ductal cancer

Answer 13

Upper outer quadrant
TIMM
Tubular
Inflammatory
Mucinous
Medullary

Question 14

Lobular CIS AND invasive breast cancer

Answer 14

Loss of E-cadherin

Question 15

Level I axillary lymph node spread

Answer 15

Lateral to pec minor

Question 16

Level II axillary lymph node spread

Answer 16

At pec minor

Question 17

Level III axillary lymph node spread

Answer 17

Medial to pec minor

Question 18

Triple -ve breast ca

Answer 18

Poor prognosis
Young females
African

Question 19

Traszutumab

Answer 19

HER 2
Need echo

Question 20

Male breast ca

Answer 20

BRCA 2
Kleinfelter’s syndrome