brain tumours Flashcards

1
Q

presentation

A

focal neurology based on location

featured of raised ICP

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2
Q

causes of raised ICP

A

tumours
intracranial haemorrhage
idiopathic intracranial htn
ascbess or infection

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3
Q

features of raised ICP

A
headache
alt mental state
visual field defects
seizures
unilateral ptosis
3rd + 6th N palsies
papilloedema
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4
Q

features of raised ICP - headache

A

constant
nocturnal
worse when coughing, straining, bending forwards
vomit

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5
Q

papilloedema

A

swelling of optic disc 2ry to raised ICP

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6
Q

papilloedema - fundoscopic changes

A
blurred optic disc margin 
elevated optic disc
loss venous pulsation 
engorged retinal veins
haemorrhages
patons lines
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7
Q

types of brain tumours

A
2ry mets
gliomas
meningiomas
pituitary tumours
acoustic neuromas
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8
Q

most common cancers which metastasise to brain

A

lung
breast
renal cell carcinoma
melanoma

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9
Q

gliomas

A

tumours of glial cell sin brain or spinal cord

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10
Q

gliomas - types

A

astrocytoma
oligodengroglioma
ependymoma

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11
Q

Meningiomas

A

tumours growing from cells of meninges

usually benign

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12
Q

pituitary tumours

A

tend to be benign

can press on optic chiasm –> bitemporal hemianopia

potential to cause hormone deficiencies or excess hormones

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13
Q

pituitary tumours - can lead to (hormone issues)

A

acromegaly
hyperprolactinaemia
cushing’s
thyrotoxicosis

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14
Q

acoustic neuroma

A

tumours of schwann cells surrounding auditory nerve

occur at cerebellopontine angle

bilateral assoc w neurofibromatosis 2

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15
Q

acoustic neuroma - classic symptoms

A

hearing loss
tinnitus
balance problems

can also be assoc w FN palsy

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16
Q

Treatment of Pituitary Tumours - prolacitn secreting

A

bromocriptine

17
Q

Treatment of Pituitary Tumours - GH secreting

A

somatostatin analogues e.g. ocreotide