Brain organization

Question 1

damage to hippocampus results in

Answer 1

anterograde memory deficit. No loss of memory, just disability to form new memories

Question 2

what forms the BBB

Answer 2

tight jxns b/w endothelial cells, pericytes, and astroglial foot processes.

Question 3

What areas of the brain lack a BBB? give two specific examples

Answer 3

circumventricular organs; pineal gland and area postrema (emetic center)

Question 4

local interneurons are often___ and use ___. projection neurons are often____ and use ___.

Answer 4

inhibitory, GABA. Excitatory, glutamate

Question 5

four major neuromodulators of brain and where they affect

Answer 5

dopamine (basal ganglia,cerebrum) , NE, Serotonin, ACh (last three go basically everywhere)

Question 6

Source of dopamine secretion. Loss of what part results in what dz?

Answer 6

substantia nigra. Loss of pars compacta results in parkinsons

Question 7

Source of NE in brain? Source of Serotonin? histamine? ACh?

Answer 7

Locus ceruleus of pons. Raphe nuclei of brainstem. Hypothalamus. Basal nuclei of forebrain.

Question 8

three main brain pathway loops and their functions

Answer 8

Basal ganglia loop: selection/reward of movement.
Cerebellar: guidance/termination of movement.
Limbic: consolidation of memory

Question 9

what type of organization do the brain loops have

Answer 9

topographic