Blood, tissue fluid & lymph 8.3 Flashcards
what is the function of blood plasma
it carries a variety of other components including dissolved glucose and amino acids, mineral ions, hormones and the large plasma proteins including albumin, fibrinogen and globulins.
Plamsa also transports red blood cells and the many different types of white blood cells and also platelets
what are platelets
Platelets are fragments of large cells called megakaryocytes found in the red bone marrow, and they are involved in the clotting mechanism of the blood.
What percentage of the blood is plasma
Plasma makes up 55% of the blood by volume
Name examples of what the blood transports
-Oxygen to, and carbon dioxide from, the respiring cells
-Digested food from the small intestine
-Nitrogenous waste products from the cells to the excretory organs
-Chemical messages (hormones)
-Food molecules from the storage compounds to the cells that need them
-Platelets to damaged areas
-Cells and antibodies involved in the immune response
what are fenestrations
it means the gaps or openings
What can pass through the capillary walls from blood plasma
The substances dissolved in plasma can pass through the fenestrations in the capillary walls, with the exception of the large plasma proteins
what is oncotic pressure
Oncotic pressure is the tendency of water to move into the blood by osmosis
-3.3 kPa
How does albumin link to oncotic pressure
The plasma protein albumin has an osmotic effect. They give the blood in the capillaries a relatively low water potential compared to the surrounding fluid. As a result water has a tendency to move into the blood in the capillaries from the surrounding fluid by osmosis
what is hydrostatic pressure
As blood flows through the arterioles into the capillaries, it is still under pressure from the surge of blood that occurs every time the heart contracts
How does hydrostatic pressure effect the arterial end of the capillary
At the arterial end of the capillary, the hydrostatic pressure forcing fluid out of the capillaries is relatively high at about 4.6 kPa. It is higher than the oncotic pressure attracting water in by osmosis, so fluid is squeezed out of the capillaries
what is tissue fluid
The fluid squeezed out of the capillary by the high hydrostatic forces that fills the space between the cells
what is the composition of tissue fluid
Tissue fluid has the same composition as the plasma, without the red blood cells and the plasma proteins. Diffusion takes place between the blood and the cells through the tissue fluid
Explain what happens to the blood as it moves through the capillary and what happens to the forces that act on the environment
As the blood moves through the capillaries the hydrostatic pressure falls to around 2.3 kPa in the vessels as fluid has moved out and the pulse in completely lost.
The oncotic pressure is still -3.3kPa, so it is now stronger than the hydrostatic pressure, so water moves back into the capillaries by osmosis as it approaches the venous end of the capillaries.
By the time the blood returns to the veins, 90% of the tissue fluid is back in the blood vessels
What happens to the 10% of the tissue fluid that does not return to the capillaries
10% of the liquid that leaves the blood vessels drains into a system of blind-ended tubes called lymph capillaries, where it is known as lymph.
what is the composition of lymph
Lymph is similar in composition to plasma and tissue fluid but has less oxygen and fewer nutrients, it also contains fatty acids which have been absorbed into the lymph from the villi of the small intestine