Blood Chemistry: Liver: Bilirubin Flashcards
1
Q
What is bilirubin?
A
Metabolite of hemoglobin
2
Q
Describe Bilirubin before it goes through the liver? (2)
A
Unconjugated
Insoluble in water
3
Q
Describe Bilirubin after it goes through the liver? (2)
A
Conjugated
Soluble in water
4
Q
What is conjugated Bilirubin also known as?
A
Direct
5
Q
What is unconjugated Bilirubin also known as?
A
Indirect
6
Q
How do you calculate unconjugated (indirect) Bilirubin?
A
Total Bilirubin - direct = indirect
7
Q
What causes increased conjugated Bilirubin? (3)
A
- Hepatocellular damage
- Bile duct obstruction or injury
- Cellular swelling
8
Q
What causes increased unconjugated Bilirubin? (2)
A
- Excessive RBC destruction
2. defects in transportation of Bilirubin into liver
9
Q
What can increased unconjugated Bilirubin indicate?
A
May indicate early liver disease
