Biochem Mnemonics Flashcards
Catabolism steps of branched chain amino acids.
“Truck hit the Ox to Death”
Essential amino acids.
“PVT. TIM HALL always argues, never tires”
Phenylalanine, Valine, Threonine, Tryptophan, Histidine, Arginine, Leucine, Lysine
(always ARGues = ARGinine, not Asparagine)
(never TIRes = not TYRosine, but tryptophan and threonine)
Names of types I - VI of Glycogen storage.
"Viagra Pills Cause A Major Hardon" Von gierke's Pompe's Cori's Anderson's Mcardles's Her's
Glycolysis steps.
“Goodness Gracious, Father Franklin Did Go By Picking Pumpkins (to) Prepare Pies”
Glucose, Glucose -6 -P, Fructose-6-P, Fructose-1,6-diP, Dihydroxyacetone-P, Glyceraldehyde-P, 1,3-Biphosphoglycerate, 3-Phosphoglycerate, 2-Phophoglycerate, Phosphoenolpyruvate (PEP), Pyruvate
Niacin deficiency syptoms.
the 4 D's Diarrhea Dermatitis Dementia Death (if untreated)
When is the Phosphorylation cascade active?
“In the “Ph”asting state, Phosphorylate.”
active when blood glucose is low
Type 1 glycogen storage disease.
“Type 1 = one (Von)”
as in Von Gierke’s disease
Does the Van den Bergh reaction (Jaundice test of indirect reacting bilirubin) involve conjugated or unconjugated bilirubin?
“Indirect reacting bilirubin = Unconjugated bilirubin”
both start with vowels
Symptoms of the Vit B3 (niacin, nicotinic acid) deficiency known as Pellagra.
"the 3 D's of pellagra" Dermatitis Diarrhea Dementia (note vit B(3) is the (3) D's
The common Coagulation pathway (the factors in order).
“10 + 5 - 2 = 13”
Factor X to Factor V to Factor II to Factor XIII
Symptoms of Fabry’s disease.
“FABRY’S”
Foam cells in glomeruli / Febrile episodes
Alpha galactosidase A deficiency / Angiokeratomas
Burning pain in extremities
Renal failure
YX genotype (male, X linked recessive)
Sphingolipidoses
In heme synthesis, what are the precursor amino acids?
“Dracula wants to Suck a Co-ed’s blood (think heme) with his Glystening teeth.”
Succinyl CoA and Glycine are precursor amino acids to pyrole rings (the basic unit of porphyrins and heme).
What causes a hemoglobin binding curve to shift right?
"CADET, face right!" CO2 Acid 2,3 DPG (aka 2,3 BPG) Exercise Temperature
How are amino acids involved in Sickle cell anemia?
“HBS isn’t Very Good”
at Sixth position of HB beta chain, Valine is present instead of Glutamic acid
Position on the beta chain that is affected in Sickle cell anemia.
“SICKle cell is due to a amino Substitution at the SICKsth position”
Vitamin K dependent cofactors.
“Several Tend To Nicely Stop Clots”
factor VII, X, II, and IX
protein S and C
Adrenaline mechanism.
“ABC of Adrenaline”
Adrenaline activates Beta receptors then increases Cyclic AMP
Mechanism that Glucagon uses to increase blood glucose.
“Mr. Gluca has GONe to the cAMP to bring out some Glucose”
glucagon elevates blood glucose by using cAMP mechanism
3 classic signs of Hyperglycemia.
“DKA”
Dehydrated
Ketoacidosis
Acetone breath
Amino acid precursers for Creatine phosphate.
"Nice GAMs!" Glycine Arginine Methionine (gams are slang for women's legs)
Amino acids forming AcetylCoA and AcetoacetylCoA.
"A Lighter Lease (A LyTr LeIs)" A = AcetylCoA or AcetoacetylCoA Ly = Lysine Tr = Tryptophan Le = Leucine Is = Isoleucine
Carbon monoxide’s target in the electron transport. chain.
“CO blocks CO”
Carbon monoxide blocks Cytochrome Oxidase
Citric acid cycle components.
“Can I Keep Selling Sex For Money, Officer?”
Citrate, Isocitrate, alpha Kergluterate, Succinyl CoA, Succinate, Fumerate, Malate, Oxaloacetate
Strongest DNA bonds.
“Crazy Glue”
Cytosine and Guanine (3 H bonds)
(A=T only has 2 H bonds and b/c it’s weaker this is where the RNA primer makes the initial break)
In the electron transport chain, at which complex site is the Rotenone’s site of action?
“RotenONE is a site specific inhibitor of complex ONE”
In which is there a change in Vmax / Km?
Competitive or Non-competitive inhibition
“Kompetitive - Km increases; no change in Vmax”
“Non-Kompetitive - No change in Km; but Vmax decreases”
Functions of the Golgi complex.
“Golgi Distributes A SPAM”
Distributes proteins and lipids from ER
Add mannose onto specific lysosome proteins
Sulfation of sugars and selected tyrosine
Proteoglycan assembly
Add O-oligosugars to serine and threnonine
Modify N-ologasugars on asparagine
Malate-asparate shuttle.
“MAD commute”
Malate in
Alpha-ketoglutarate and D (aspartate) out
What 3 processes happen in both, the cytosol and mitochondria metabolic sites?
‘Use both arms to HUG”
Heme synthesis
Urea cycle
Gluconeogenesis
Number of Na and K in and out in the Na/K pump.
song (Kiss him goodbye) - “Na Na Na Out, Na Na Na Out, K K Goes…Inside”
(pump moves 3 Na out, 2 K in)
Amino acid precurser for Nitric oxide.
You yell “AAArg!” at the dentist, so he gives you Nitric Oxide for the pain.
What is Pompe’s disease?
“Police = Po + Lys”
Pompe’s disease is a Lysosomal storage disease
Products of complete oxidation of Pyruvate.
"4 Naked Fun, 3 Coeds + 1 Guy" 4 NADH FADH 3 CO2 1 GTP
Symptom of Tangier’s disease.
“Tangierene tonsils”
large orange tonsils
