BCM31

Question 1

Overton

Answer 1

observed only lipophillic enter cell

Question 2

langmuir

Answer 2

studied monolayers in eponymous troough

Question 3

eponymous trough

Answer 3

requires pure water so doesnt interfere with membrane

Question 4

Nmm^2 RBC lipid covers -> off trough

Answer 4

2Nmm^2 = bilayer

Question 5

Gorter and grender

Answer 5

bilayer

Question 6

miscelles

Answer 6

phospholipid shaken with water - suspensions of misclles

Question 7

roles

Answer 7

compartmentalisation
transmission and detection of signals
regulate transport

Question 8

black lipid membrane

Answer 8

aperture made with teflon painted with lipid

- sim thickness to lipid but differ electrically

Question 9

davson and danielli

Answer 9

lipid sandwhich
protein bread
lipid filling

Question 10

robertson

Answer 10

interpret electron micrographs
= 7nm thick
unit membrane
freeze fracture consistent

Question 11

lateral diffusion of lipid

Answer 11

rapid

Question 12

transverse diffusion of lipid

Answer 12

slow

Question 13

mouse cell + human cell

proof

Answer 13

heterokaryon
- mixed after hour
proteins mix on surface

Question 14

singer nicholson

Answer 14

fluid mosaic mode

Question 15

sonicated at 20kh

Answer 15

membranes break into liposomes

drug transport

Question 16

composition myelin nerve sheath

Answer 16

protein 18%
lipid 79%
carb 3%

Question 17

composition erthrocyte

Answer 17

protein 49%
lipid 43%
carbohydrate 8%

Question 18

chloroplast composition

Answer 18

protein 70%

lipid 30%

Question 19

mitochondrion composition

Answer 19

protein 76%

lipid 24%

Question 20

lipid rafts

Answer 20

may mean refinement neccesary

1. more ordered than surroundings
2. float freely in membrane
3. 3/5 X more cholesterol
4. enriched in sphingolipids 50% more
5. long term stability

Question 21

differences between blm and natural

Answer 21

thickness = nat 4-12 black 5-10

resistence nat 10^6-10^9 blm 10^7 -10^13