Bacteriology- Gram negative cocci

Question 1

N meningitidis vs N gonorrheae fermentation

Answer 1

Meningitidis- Glucose, maltose
Gonococcus- Glucose

Question 2

Shape of Neisseria sp

Answer 2

Meningitidis- lens shaped with capsule
Gonorrhoea- kidney shaped

Question 3

Catalase, oxidase status of Neisseria sp

Answer 3

Both are catalase and oxidase positive

Question 4

Neisseria oxygen requirement

Answer 4

Meningitidis- strict aerobe
Gonorrhoea- facultative anaerobe

Question 5

Virulence factors for N. meningitidis

Answer 5

Capsular polysaccharide A, B, C, Y, W135
IgA protease
Endotoxin
Type IV pili
Outer membrane protein

Question 6

Virulence factors for N. gonococcus

Answer 6

Capsular polysaccharide A, B, C, Y, W135
IgA protease
Endotoxin
Type IV pili
Outer membrane protein, protein I (PORB1a, PORB1b), protein II

Question 7

Transport media for Neisseria

Answer 7

Stuart/ Amies media

Question 8

Culture media for Neisseria

Answer 8

Modified Thayer martin medium

Question 9

Treatment for Meningitidis

Answer 9

Ceftriaxone IV

Question 10

Treatment for Gonococcus

Answer 10

Ceftriaxone IV
Azithromycin

Question 11

Waterhouse friedrichsen syndrome

Answer 11

D/t N. meningitidis
B/l adrenal hemorrhage

Question 12

Clinical features of Gonococcus

Answer 12

Ophthalmia neonatorum
Urethritis in males
Cervicitis in females- watercan perineum

Question 13

Complications d/t Gonococcus infection

Answer 13

Fitz Hugh Curtis Syndrome
Disseminated Gonococcal infection d/t PORB1a

Question 14

Meningococcal vaccine doesnt provide protection against

Answer 14

B serotype

Question 15

Modified Thayer martin medium contains

Answer 15

Nystatin
Colistin
Vancomycin
Trimethoprim

Old one didnt have Trimethoprim

Question 16

Moraxella catarrhalis causes

Answer 16

Otitis media
Exacerbations in COPD (2nd MC)

Question 17

Culture characteristic of Moraxella catarrhalis

Answer 17

Hockey Puck sign- colonies can be moved around the media