B7 L1 Flashcards
Glomerular Capillaries
filters plasma into nephron
makes tubular fluid
fed by afferent, drained by efferent arteriole
Peritubular Capillaries
fed by efferent
needed for reabsorption and secretion
Filtration
filter plasma to make tubular fluid (urine)
Filtered Load
amount filtered in capillaries
Excretion
removed in urine
what is left in nephron after filtration
Reabsorption
move solute/ water back into blood
Secretion
move solute from blood to tubular fluid
Bowman’s Capsule
entrance to nephron
surrounds glomerulus
Proximal Convoluted Tubule
reabsorbs majority of ions and water, and all glucose and AA
Loop of Henle
reabsorption and dilution of urine
makes gradient to alter urine conc
Descending Limb of Loop of Henle
water reabsorption
no solute mvmt
Ascending Limb of Loop of Henle
Solute reabsorption
no water mvmt
Macula Densa
senses tubular fluid flow and renal blood flow
regulates afferent/ efferent arteriole size
Distal Convoluted Tubule
reabsorption and secretion of ions
fine tuning of urine solute amounts
pH balance
Thiazide
diuretic affecting DCT
Carbonic Anhydrase Inhibitor
diuretic affecting PCT
Furosimide
diuretic affecting Loop of Henle
Collecting Ducts
control water loss/ reabsorption and urine osmolarity
site of Anti-diuretic hormone function
Potassium Sparing Diuretics
affect Collecting Ducts
Renal Input
Renal Artery
Renal Output
Renal Vein and Ureter
Clearance
how much plasma has solute removed in 1 min
determine amount of plasma filtered and amount of blood delivered to kidney
Clearance Formula
Xu * V / Xa
Clearance of Inulin
Glomerular Filtration Rate
amount of plasma filtered
inulin is only filtered
Clearance of PAH
Renal Plasma Flow
100% filtered and 100% secreted
how much plasma moved through kidney
Filtration Fraction
amount of plasma filtered by kidney
=GFR/RPF
Free Water Clearance
how much water is excreted
vol of all solutes removed
High Plasma Osmolarity
excrete as little water as possible
dilute solutes
Low Plasma Osmolarity
excrete lots of dilute water
Free Water Clearance Formula
Cosm= (Uosm * V) / Posm
Positive Free Water Clearance
more water cleared than solutes
because body overhydrated, ECF osmol low
Negative Free Water Clearance
more solute cleared than water
because body dehydrated, ECF osmol high
Uosm»_space;> Posm
Negative Cwater
need to keep water in body
Uosm «< Posm
Positive Cwater
need to lose water