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Pharmacology Semmelweis > B - 18. Drugs used for the treatment of hypertension II: Ca++-channel blockers and other vasodilators > Flashcards

B - 18. Drugs used for the treatment of hypertension II: Ca++-channel blockers and other vasodilators Flashcards

1
Q

Indications for CCB

A

Hypertension

Angina (decreases oxygen demand and increases supply (vasodialation))

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2
Q

Dihydropyridines names

A

Nifedipine
Amlodipine
Felodipine
Nimodipine

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3
Q

Dihydropyridines action

A

Acts mainly on smooth muscle cells of vessels, causes vasodialation

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4
Q

Dihydropyridines SE

A

Reflex tachycardia in high doses

Vasodialation -> hypotension -> baroreceptors sense it and increase sympathetic firing to heart -> increased heart rate

Gingeval hyperplasia

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5
Q

Non-dihydropyridines names and effect

A

Verapamil

greater effect on heart than vessels

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6
Q

cGMP-mediated vasodialators names

A

dihydralazine

sildenafil

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7
Q

cGMP-mediated vasodialators action

A

Increase cGMP -> vasodialation

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8
Q

Pulmonary hypertension vasodialator

A

bozentan

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Pharmacology Semmelweis (42 decks)

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