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Pharmacology Semmelweis > A - 7. Mineralocorticoids. Topically applied glucocorticoids > Flashcards

A - 7. Mineralocorticoids. Topically applied glucocorticoids Flashcards

1
Q

Main function

A

Increase blood volume (upregulates Na+/K+ATPase on principal cells in distal conv. tubule, increasing Na+ reuptake into blood -> increased blood volume)

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2
Q

Mineralocorticoids (non-topical); names

A

Fludrocortizone (mineralocorticoid defficiency)

SE - edema, iatrogenic cushings

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3
Q

Topical and nasal glucocorticoids

A

fluocinolon
mometazone
budesonide
fluticazone

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4
Q

Glucocorticoid inhibitors

A

Metyrapone

Hypertension, edema, hyperaldosteronism, reduces mortality after MI

SE

  • arrythmia due to hyperkalemia
  • impotence, gynecomastia
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Pharmacology Semmelweis (42 decks)

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