A - 18. Drugs used in coagulation disorders III: Fibrinolytic drugs. Drugs used in bleeding disorders Flashcards
1
Q
tPA derived drugs
A
Alteplase
Reteplase
Binds to fibrin and plasminogen in clot –> activates plasmin -> fibrin mesh yeet
2
Q
From bacteria
A
Streptokinase
Can trigger immune response
Binds to plasminogen in circulation
3
Q
Drugs to counter bleeding disorders
A
epsilon-amino-caproic acid - used in bleeding from elevated fibrinolytic activity
vitamin K - anti-warfarin
epinephrine
fibrin foam - contains human fibrinogen and thrombin