A - 18. Drugs used in coagulation disorders III: Fibrinolytic drugs. Drugs used in bleeding disorders Flashcards

1
Q

tPA derived drugs

A

Alteplase
Reteplase

Binds to fibrin and plasminogen in clot –> activates plasmin -> fibrin mesh yeet

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2
Q

From bacteria

A

Streptokinase

Can trigger immune response
Binds to plasminogen in circulation

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3
Q

Drugs to counter bleeding disorders

A

epsilon-amino-caproic acid - used in bleeding from elevated fibrinolytic activity

vitamin K - anti-warfarin

epinephrine

fibrin foam - contains human fibrinogen and thrombin

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