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Drug of the Day - CPT > Azathioprine > Flashcards

Azathioprine Flashcards

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NASM ® CPT flashcards
1
Q

What class is Azathioprine?

A

Immunosuppressant (disease modifying drug)

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2
Q

What are the common indications for Azathioprine?

A
  • SLE and vasculitis - maintenance therapy
  • IBD
  • Atopic dermatitis
  • Bullous skin disease
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3
Q

What is the mechanism of action of Azathioprine?

A

Anti-proliferative

decreases DNA and RNA synthesis (inhibition of de novo purine synthesis)

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4
Q

What are the common adverse reactions of Azathioprine?

A
  • Myelosuppression (bone marrow suppression) - monitor FBC
  • Increased risk of malignancy (especially if had a transplant)
  • Increased risk of infection
  • Hepatitis - monitor LFTs
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5
Q

What are the common drug-drug reactions of Azathioprine?

A
  • Other immunosuppressants
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Drug of the Day - CPT (27 decks)

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