Autoantibody Flashcards

1
Q

anti-p155

A

dermatomyositis
also associated wth cancer of stomach, breast, gallbladder

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2
Q

anti-Jo1

A

inflammatory myopathy

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3
Q

anti-SRP

A

polymyositis

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4
Q

anti-smith

A

SLE

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5
Q

anti-histone

A

drug induced SLE

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6
Q

U1RNP antibody

A

mixed connective tissue disease

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7
Q

Anti-MDA-5

A

dermatomyositis + rapidly progressive lung disease

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8
Q

Anti-Mi-2

A

dermatomyositis + severe muscle disease

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9
Q

Anti-NXP-2

A

young onset dermatomyositis, or disease associated with malignancy in adults

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10
Q

Anti-HMGCR

A

immune-mediated necrotising myopathy
associated in 50% of cases with statin use

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11
Q

anti-mitochondrial antibodies

A

primary biliary cirrhosis

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