Autoantibody Flashcards
Anti-glutamic acid decarboxylase antibodies (anti-GAD)
stiff-person syndrome
diabetes
N-methyl-D-aspartate receptor (NMDAR) antibodies
autoimmune enchephalitis
contactin-associated protein-like (Caspr2) antibodies
autoimmune enchephalitis
autoimmune epilepsy
anti-yo antibodies
paraneoplastic cerebellar degeneration
anti-p155
dermatomyositis
also associated wth cancer of stomach, breast, gallbladder
anti-Jo1
inflammatory myopathy
anti-SRP
polymyositis
anti-smith
SLE
anti-aquaporin 4 (NMO-IgG) antibodies
neuromyelitis optica spectrum disorder
can also be seen in classic MS
anti-LGL1
limbic encephalitis
faciobracial seizures + MRI changes, memory loss, behavioural changes
anti-NMDA
anti-NMDA receptor enchepalitis
often fever, headache, tired
can be triggered by HSV
presence of IgG
AChR antibodies
myasthenia graves
85%
MuSK antibodies
myasthenia graves
8%
more bulbar than systemic
anti-histone
drug induced SLE
U1RNP antibody
mixed connective tissue disease