RACP-Endocrine Flashcards
Which insulin has the longest half-life?
A. Lispro
B. Aspart
C. Neutral protamine hagedorn
D. Glargine
E. Detamir
D- glargine (12-24 hours)
Which of these hormones acts via an intracellular receptor?
A. Insulin
B. Glucagon
C. Cortisol
D. ACTH
E. TSH
C. Cortisol
A 54 year old woman presents with severe menopausal symptoms, amenorrhoea for 14 months. She is normally fit and well and wants to pursue HRT. What is the best option for managing her symptoms?
A. Oestrogen and cyclical progesterone
B. Oestrogen with continual progesterone
C. Topical oestrogen
D. Oral oestrogen only
B. Oestrogen with continual progesterone
Which of the following conditions is it most likely to achieve euthyroidism after effective radioactive iodine therapy?
A. Graves’ disease
B. Autonomous nodule
C. Thyroid cancer
D. Multinodular goitre
B. Autonomous nodule
- Apart from age, what is the most prevalent risk factor for erectile dysfunction
A) Drug side effects
B) Hypogonadism
C) Neurological
D) Vascular
D) Vascular
- The use of bisphosphonates after cessation of denosumab is to reduce rapid bone loss and prevent increased fractures of:
A) Distal radius
B) Intertrochanteric
C) Subcapital neck of femur
D) Vertebral
D) Vertebral
2021
Q9. A 46 year old woman with Addison’s disease presents with flank pain and dysuria. Her maintenance
medications are hydrocortisone 10mg twice daily and fludrocortisone 100mcg daily. Her temperature is 38.4C, BP
is 124/76 and her heart rate is 106. She is diagnosed with pyelonephritis and admitted for IV antibiotics. She is
tolerating oral intake.
What is the best plan for her regular medications?
A. Add prednisone 20mg daily
B. IV hydrocortisone 100mcg three times daily
C. Increase oral hydrocortisone to 20mcg twice daily
D. Increase oral hydrocortisone to 20mcg twice daily and fludrocortisone to 200mcg daily
This question and the answer options were well recalled.
C. Increase oral hydrocortisone to 20mcg twice daily
Q33. What are the two other Rotterdam criteria for PCOS, in addition to an ultrasound finding of polycystic
ovaries?
A. Increased LH:FSH ratio and clinical evidence of hyperandrogenism
B. Increased LH:FSH ratio and primary infertility
C. Oligo/anovulation and clinical evidence of hyperandrogenism
D. Oligo/anovulation and insulin resistance
C. Oligo/anovulation and clinical evidence of hyperandrogenism
Q39. In a type 1 diabetic with a HbA1c of 8.6% currently without retinopathy, what is the chance of proliferative
retinopathy developing within the next 5 years?
A. 0.5%
B. 5%
C. 25%
D. 50%
C. 25%
Q57. A 57 year old female who has completed a 6 month course of pembrolizumab for metastatic melanoma has
routine follow up bloods done. She has had an excellent treatment response and has had minimal side effects
from treatment. You notice her thyroid function tests have changed:
TSH 38.2
(T3/T4 not recalled – essentially bloods consistent with hypothyroidism)
What is the most appropriate course of management?
A. Commence levothyroxine replacement
B. Commence prednisone
C. Technetium scan
D. Cease pembroluzimab
A. Commence levothyroxine replacement
Q76. What complication can you avoid in a patient being given topical oestrogen as opposed to oral oestrogen,
in a patient with functional hypothalamic amenorrhea requiring oestrogen replacement?
A. Low BMD
B. Infertility
C. Genital atrophy
D. Endometrial hypertrophy
D. Endometrial hypertrophy
Q83. A 35 year old woman has an 8 month history of amenorrhoea and galacterrhoea. She presents with
retrorobital pain, unilateral oculomotor palsy and hypotension. What is the most appropriate treatment?
A. Cabergoline
B. Desmopressin
C. Hydrocortisone
D. Levothyroxine
C. Hydrocortisone
2021
Q87. What is the most appropriate test to diagnose suspected secondary adrenal insufficiency in an elderly
patient?
A. Morning ACTH and cortisol
B. Serum cortisol measured 30 minutes after synthetic ACTH administration (short synacthen test)
C. Serum cortisol measured 30 minutes following insulin-induced hypoglycaemia (insulin tolerance test)
D. Serum cortisol measured 72 hours after synthetic ACTH administration (long synacthen test)
This question and the answer options were well recalled.
B. Serum cortisol measured 30 minutes after synthetic ACTH administration (short synacthen test)
Q93/Q94 EMQ – Match the following genetic cancer syndromes from the list of options:
A. MEN1
B. RET
C. VHL
D. SDHA
E. SDHB
F. HPNCC
G. MLH1
H. PTEN
I. PKP2R*
J. NF1*
*Not sure if these two were options.
Q93. Patient presents with pancreatic cancer, pituitary adenoma and hyperparathyroidism
Q94. Patient presents with retinal angioblastoma, cerebellar hemangioma and a large renal mass.
q93- A MEN1
q94- C VHL
2021
Q9. A 46 year old woman with Addison’s disease presents with flank pain and dysuria. Her maintenance
medications are hydrocortisone 10mg twice daily and fludrocortisone 100mcg daily. Her temperature is 38.4C, BP
is 124/76 and her heart rate is 106. She is diagnosed with pyelonephritis and admitted for IV antibiotics. She is
tolerating oral intake.
What is the best plan for her regular medications?
A. Add prednisone 20mg daily
B. IV hydrocortisone 100mcg three times daily
C. Increase oral hydrocortisone to 20mcg twice daily
D. Increase oral hydrocortisone to 20mcg twice daily and fludrocortisone to 200mcg daily
C. Increase oral hydrocortisone to 20mcg twice daily
