Infectious Disease

Question 1

What is the prophylaxis for malaria?

Answer 1

Atovaquone + proguanil (1-2 days before and 7 days after) OR

doxycycline (starting 1-2 days before, and continue for 4 weeks after) OR

mefloquine (once weekly for 2-3 weeks before and 4 weeks after)

Question 2

What is the management mild Malaria?

Answer 2

Artemether + lumefantrine OR

atovaquone + proguanil OR

quinine sulfate + doxy/clindamycin

Question 3

What is the management of P.Vivax + P.ovale

Answer 3

chloroquine + add primaquine for 14 days to standard regimen

Question 4

What is a side effect of primaquine?

Answer 4

haemolysis
need to check G6PD

Question 5

What is the management of severe malaria?

Answer 5

IV artesunate OR quinine diyhydrochloride

Question 6

A 32 year old man with treated HIV presents with painless ulcer on the glans penis with curled edge. He report he is still having unprotected sex.
What is the most likely cause of the legion?

A) Charcoid
B) Donovanosis
C) Herpes simplex
D) Lupus vulgaris
E) Syphilis

Answer 6

E- syphilis

*syphilis is painful ulcer
*Chancroid is often painful in men, have ragged edges
*Donovanosis- caused by klebsiella granulomatosis, rare, usually painless but can become painful. Ulcers that are beefy and bleed

Question 7

A 60year old presents febrile and neutropenic post induction chemotherapy for AML. A CT chest is concerning for fungal infection and bronchoscopy culture demonstrates Aspergillus fumigatus.

What is the most appropriate treatment?

A. Posaconazole
B. Fluconazole
C. Itraconazole
D. Carbimazole
E. Voriconazole

Answer 7

E. Voriconazole

Question 8

A urinalysis was positive for leukocytes but negative for nitrites. A microorganism was grown on culture. Which microorganism is it most likely?

A. Pseudomonas aeruginosa
B. Enterococcus faecalis
C. E.coli
D. Enterobacter cloacae
E. Klebsiella pneumoniae

Answer 8

B. Enterococcus faecalis

think gram +ve