atherosclerosis Flashcards
1
Q
what is atheroscleorsis
A
atheroma - fatty deposits in artery walls
sclerosis - hardening/stiffening
2
Q
development of atheromatous plaque
A
fatty streak –> early atheromatous plaque –> fully developed atheromatous plaque
3
Q
pathophys atherosclerosis
A
chronic inflammation and immune system activation –> lipid deposition
central lipid core with fibrous tissue plaque
inflammatory cells
4
Q
what does atheroscelrosis cause
A
stiffening –> htn
stenosis –> reducded blood flow
plaque rupture –> thrombus
5
Q
risk factors
A
FHx male age alcohol smoking poor diet lack exercise stress diabetes htn CKD RA
6
Q
end results
A
angina
MI
TIA/Stroke
PVD
7
Q
2ry prevetion once disease developed
A
statin
aspirin
beta blocker
ACE-I
