Antimicrobials – Antibacterials (Macrolides)

Question 1

What are macrolides indicated for?

Answer 1

infections caused by susceptible bacteria in the upper and lower respiratory tract, genitourinary tract, skin, and other tissues

Question 2

What is clarithromycin also used for?

Answer 2

(in combination with other medications) for H. pylori eradication in peptic ulcer disease

Question 3

What are macrolides contraindicated in?

Answer 3

patients with hypersensitivity to macrolides

Question 4

What is clarithromycin also contraindicated in?

Answer 4

patients taking pimozide, ergotamine, or dihydroerotamine

Question 5

erythromycin (1)

Answer 5

macrolide antibiotic

• ERYC* (brand name D/C)

Question 6

Dosage Forms and Strengths

ERYC (2)

Answer 6

• ophthalmic ointment: 0.5% w/w
• pwd for injection

Question 7

azithromycin (dihydrate) (1)

Answer 7

macrolide antibiotic

• Zithromax*

Question 8

Dosage Forms and Strengths

Zithromax (3)

Answer 8

• tabs: 250 mg
• susp: 200 mg/5 mL
• pwd for injection

Question 9

Dosage Forms and Strengths

Generic Azithromycin (dihydrate) (2)

Answer 9

• tabs: 250, 600 mg
• susp: 100, 200 mg/5 mL

Question 10

azithromycin (monohydrate hemiethanolate) (1)

Answer 10

macrolide antibiotic

• Azithromycin* (brand name D/C)

Question 11

Dosage Forms and Strengths

Azithromycin (1)

Answer 11

tab: 250 mg

• l = mg azithromycin, but actual form present is azithromycin monohydrate hemiethanolate

Question 12

clarithromycin (3)

Answer 12

macrolide antibiotic

• Biaxin*
• Biaxin BID*
• Biaxin XL* (brand name D/C)

Question 13

Dosage Forms and Strengths

Biaxin (1)

Answer 13

susp: 125 mg, 250 mg/5 mL

Question 14

Dosage Forms and Strengths

Biaxin BID (1)

Answer 14

tabs: 250, 500 mg

Question 15

Dosage Forms and Strengths

Generic Clarithromycin (1)

Answer 15

ER tabs: 500 mg