Antimicrobials – Antibacterials (Aminoglycosides)

Question 1

What are aminoglycosides indicated for?

Answer 1

infections caused by susceptible bacteria in the respiratory tract, urinary tract, bone, skin and other tissues

Question 2

What are aminoglycosides comtraindicated in?

Answer 2

patients with hypersensitivity

Question 3

gentamicin (1)

Answer 3

aminoglycoside antibiotic

• Gentamicin Injection*

Question 4

Dosage Forms and Strengths

Gentamicin Injection (1)

Answer 4

injection soln: 10, 40 mg/mL

Question 5

tobramycin (2)

Answer 5

aminoglycoside antibiotic

• Tobrex* (eye drops available as generic)
• Tobramycin Injection*

Question 6

Dosage Forms and Strengths

Tobrex (2)

Answer 6

• ophthalmic oint: 0.3% w/w
• ophthalmic soln: 0.3% w/v

Question 7

Dosage Forms and Strengths

Tobramycin Injection (3)

Answer 7

• pwd for injection
• injection soln: 10, 40 mg/mL
• inhalation soln: 60 mg/mL, 300 mg/5 mL

Question 8

tobramycin / dexamethasone (1)

Answer 8

aminoglycoside antibiotic – topical corticosteroid

• Tobradex

Question 9

Dosage Forms and Strengths

Tobradex (2)

Answer 9

• ophthalmic ointment: 0.3% w/w tobramycin + 0.1% w/w dexamethasone
• ophthalmic suspension: 0.3% w/v tobramycin + 0.1% w/v dexamethasone