Anti-Gout Agents Flashcards
1
Q
What is colchicine indicated in?
A
treatment of acute gout attacks and chronic gout
2
Q
What is allopurinol and febuxostat indicated in?
A
urate-lowering therapy in the treatment of chronic gout
3
Q
What is colchicine contraindicated in? (3)
A
- patients with renal or hepatic impairment
- active peptic ulcer or serious gastrointestinal disease
- patients taking other medication that are CYP3A4 or P-glycoprotein inhibitors
4
Q
What are all anti-gout agents contraindicated in?
A
patients with hypersensitivity
5
Q
What is febuxostat contraindicated in?
A
patients taking azathioprine or mercatopurine
6
Q
allopurinol (1)
A
xanthine oxidase inhibitor
- Zyloprim* (brand name D/C)
7
Q
Dosage Forms and Strengths
Zyloprim (1)
A
tabs: 100, 200, 300 mg
8
Q
colchicine (1)
A
antimitotic
- Colchicine*
9
Q
Dosage Forms and Strengths
Colchicine (1)
A
tabs: 0.6 mg
10
Q
febuxostat (1)
A
xanthine oxidase inhibitor
- Uloric* (brand name D/C)
11
Q
Dosage Forms and Strengths
Uloric
A
tabs: 80 mg
