Antimicrobials – Antibacterials (Fluoroquinolones)

Question 1

What are fluoroquinolones indicated for?

Answer 1

infections caused by susceptible bacteria in the upper and lower respiratory tract, urinary tract, skin, prostate (ciprofloxacin only), and other tissues

Question 2

What are fluoroquinolones contraindicated in?

Answer 2

patients with hypersensitivity to fluoroquinolones or benzalkonium chloride (eye drops only)

Question 3

What is ciprofloxacin contraindicated in?

Answer 3

patients taking tizanidine

Question 4

ciprofloxacin (1)

Answer 4

fluoroquinolone antibiotic

• Cipro*

Question 5

Dosage Forms and Strengths

Cipro (2)

Answer 5

• susp: 500 mg/5 mL
• IV soln: 2 mg/mL

Question 6

ciprofloxacin hydrochloride (3)

Answer 6

fluoroquinolone antibiotic

• Cipro**
• Cipro XL**
• Ciloxan**

Question 7

Dosage Forms and Strengths

Cipro (1)

Answer 7

tabs: 500 mg, 750 mg

• generic for tabs only
• mg ciprofloxacin, but actual form present is ciprofloxacin HCl

Question 8

Dosage Forms and Strengths

Cipro XL (1)

Answer 8

ER tabs: 500 mg

• generic for tabs only
• mg ciprofloxacin, but actual form present is a combination of ciprofloxacin and ciprofloxacin HCl

Question 9

Dosage Forms and Strengths

Ciloxan (2)

Answer 9

• ophthalmic ointment: 0.3% w/v (generic not available)
• ophthalmic solution: 0.3% w/v

(mg ciprofloxacin, but actual form present
is ciprofloxacin HCl)

Question 10

Dosage Forms and Strengths

Generic Ciprofloxacin Hydrochloride (1)

Answer 10

tabs: 250 mg

• mg ciprofloxacin, but actual form present is ciprofloxacin HCl

Question 11

ciprofloxacin / dexamethasone (1)

Answer 11

fluoroquinolone antibiotic – corticosteroid

• Ciprodex*

Question 12

Dosage Forms and Strengths

Ciprodex (1)

Answer 12

otic suspension: 0.3% w/v ciprofloxacin + 0.1% w/v dexamethasone

• mg ciprofloxacin, but actual form
  present is ciprofloxacin HCl

Question 13

levofloxacin (1)

Answer 13

fluoroquinolone

• Levaquin* (brand name D/C)

Question 14

Dosage Forms and Strengths

Generic Levofloxacin (2)

Answer 14

• tabs: 250, 500, 750 mg
• injection sln: 5 mg/mL

Question 15

moxifloxacin (3)

Answer 15

fluoroquinolone antibiotic

• Avelox* (brand name D/C)
• Avelox IV* (brand name D/C)
• Vigamox*

Question 16

Dosage Forms and Strengths

Avelox (2)

Answer 16

• tab: 400 mg
• injection soln: 400 mg/250 mL

Question 17

Dosage Forms and Strengths

Vigamox (1)

Answer 17

ophthalmic soln: 0.5% w/v

Question 18

gatifloxacin (1)

Answer 18

fluoroquinolone antibiotic

• Zymar*

Question 19

Dosage Forms and Strengths

Zymar (1)

Answer 19

ophthalmic soln: 0.3% w/v

Question 20

norfloxacin (1)

Answer 20

fluoroquinolone antibiotic

• Noroxin* (brand name D/C)

Question 21

Dosage Forms and Strengths

Generic Norfloxacin (1)

Answer 21

tabs: 400 mg

Question 22

ofloxacin (1)

Answer 22

fluoroquinolone antibiotic

• Ocuflox

Question 23

Dosage Forms and Strengths

Ocuflox (1)

Answer 23

ophthalmic soln: 0.3% w/v