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Foundations Drug List and Medical Terminology > Anticoagulants > Flashcards

Anticoagulants Flashcards

1
Q

What is anticoagulation therapy indicated for?

A

prophylaxis and treatment of venous thromboembolism

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2
Q

What are rivaroxaban and dabigatran contraindicated in?

A
  • renal insufficiency
  • when taken in combination with strong inhibitors of CYP3A4 and P-glycoprotein
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3
Q

What are low molecular weight heparins contraindicated in?

A
  • patients with a history of heparin induced thrombocytopenia (HIT)
  • should be used with caution in patients with renal dysfunction
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4
Q

What is unfractionated heparin contraindicated in?

A

patients with a history of heparin induced thrombocytopenia (HIT)

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5
Q

What is warfarin contraindicated in?

A
  • pregnancy
  • patients with hemorrhagic tendencies
  • blood dyscrasias
  • malignant hypertension
  • has a number of clinically significant drug interactions which should be assessed prior to initiation of therapy
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6
Q

warfarin (1)

A

vitamin K antagonist

  • Coumadin* (brand name D/C)
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7
Q

Dosage Forms and Strengths

Generic Warfarin (1)

A

tabs: 1, 2, 2.5, 3, 4, 5, 6, 7.5, 10 mg

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8
Q

heparin (1)

A

unfractionated heparin

  • Heparin LEO**
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9
Q

Dosage Forms and Strengths

Heparin LEO (2)

A
  • IV injection soln: 100 IU/mL (generic not available)
  • IV/SC injection soln: 1000 IU/mL (generic not available)
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10
Q

Dosage Forms and Strengths

Generic Heparin (1)

A

IV/SC injection soln: 1000, 10000 IU/mL

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11
Q

enoxaparin (2)

A

low molecular weight heparin

  • Lovenox
  • Lovenox HP
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12
Q

Dosage Forms and Strengths

Lovenox (1)

A

pre-filled syringes (SC/IV): 30 mg/0.3 mL, 40 mg/0.4 mL, 60 mg/0.6 mL, 80 mg/0.8 mL, 100 mg/mL

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13
Q

Dosage Forms and Strengths

Lovenox HP (1)

A

pre-filled syringes (SC/IV): 120 mg/0.8 mL, 150 mg/mL

(150 mg/mL)

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14
Q

What is anticoagulation therapy indicated for?

A

prophylaxis and treatment of venous thromboembolism

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15
Q

What is rivaroxaban contraindicated in?

A
  • renal insufficiency
  • when taken in combination with strong inhibitors of CYP3A4 and P-glycoprotein
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16
Q
A
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17
Q

What is dabigatran contraindicated in?

A
  • renal insufficiency
  • when taken in combination with strong inhibitors of CYP3A4 and P-glycoprotein
18
Q

What are low molecular weight heparins contraindicated in?

A
  • patients with a history of heparin induced thrombocytopenia (HIT)
  • should be used with caution in patients with renal dysfunction
19
Q

What is unfractionated heparin contraindicated in?

A

patients with a history of HIT

20
Q

What is warfarin contraindicated in?

A
  • pregnancy
  • patients with hemorrhagic tendencies
  • blood dyscrasias
  • malignant hypertension
  • has a number of clinically significant drug interactions which should be assessed prior to initiation of therapy
21
Q

warfarin (1)

A

vitamin K antagonist

  • Coumadin* (brand name D/C)
22
Q

Dosage Forms and Strengths

Generic Warfarin (1)

A

tabs: 1, 2, 2.5, 3, 4, 5, 6, 7.5, 10 mg

23
Q

heparin (1)

A

unfractionated heparin

  • Heparin LEO**
24
Q
A
25
Q

Dosage Forms and Strengths

Heparin LEO (2)

A
  • IV injection soln: 100 IU/mL (generic not available)
  • IV/SC injection soln: 1000
    IU/mL
26
Q

Dosage Forms and Strengths

Generic Heparin

A

IV/SC injection soln: 1000, 10000 IU/mL

27
Q

enoxaparin (2)

A

low molecular weight heparin

  • Lovenox
  • Lovenox HP
28
Q

Dosage Forms and Strengths

Lovenox (1)

A

pre-filled syringes (SC/IV): 30 mg/0.3 mL, 40 mg/0.4 mL, 60 mg/0.6 mL, 80 mg/0.8 mL, 100 mg/mL

29
Q

Dosage Forms and Strengths

Lovenox HP (1)

A

pre-filled syringes (SC/IV): 120 mg/0.8 mL, 150 mg/mL

30
Q

dalteparin (1)

A

low molecular weight heparin

  • Fragmin
31
Q

Dosage Forms and Strengths

Fragmin (1)

A

pre-filled syringes (SC/IV): 2500 IU/0.2 mL, 3500 IU/0.28 mL, 5000 IU/0.2 mL, 7500 IU/0.3 mL, 10,000 IU/0.4 mL, 12,500 IU/0.5 mL, 15,000 IU/0.6 mL, 16,500 IU/0.66 mL, 18,000 IU/0.72 mL, 25,000 IU/1 mL

32
Q

rivaroxaban (1)

A

direct factor Xa inhibitor

  • Xarelto*
33
Q

Dosage Forms and Strengths

Xarelto (2)

A
  • tabs: 2.5, 10, 15, 20 mg
  • granules: 1 mg/mL (when reconstituted)
34
Q

apixaban (1)

A

direct factor Xa inhibitor

  • Eliquis*
35
Q

Dosage Forms and Strengths

Eliquis (1)

A

tabs: 2.5, 5 mg

36
Q

edoxaban (1)

A

direct factor Xa inhibitor

  • Lixiana
37
Q

Dosage Forms and Strengths

Lixiana (1)

A

tabs: 15, 30, 60 mg

38
Q

fondaparinux (1)

A

indirect factor Xa inhibitor

  • Arixtra*
39
Q

Dosage Forms and Strengths

Arixtra (1)

A

injection soln: 2.5 mg/0.5 mL, 7.5 mg/0.6 mL

40
Q
A
41
Q

dabigatran (1)

A

direct thrombin inhibitor

  • Pradaxa*
42
Q

Dosage Forms and Strengths

Pradaxa (1)

A

caps: 75, 110, 150 mg

Foundations Drug List and Medical Terminology (56 decks)

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