ANTIDEPRESSANTS & ANTIPSYCHOTICS

Question 1

WHAT ARE THE 1ST GEN ANTIDEPRESSANTS?

Answer 1

“TYLINE”, DOXEPINE

Question 2

S&S OF CYCLIC ANTIDEPRESSANTS?

Answer 2

> QRS FOR UP TO 48 HOURS, ANTIHISTAMINE AND ANTICHOLINGERIC S&S

Question 3

TX OF CYCLIC ANTIDEPRESSANTS?

Answer 3

NO PHENYTOIN OR PHYSO

Question 4

WHICH CYCLIC ANTIDEPRESSANT DOES NOT CAUSE A >QRS?

Answer 4

AMOXIPINE

Question 5

WHICH NON CYCLIC ANTIDEPRESSANT HAS A LOW THERAPEUTIC INDEX AND CAUSES SEIZ?

Answer 5

BUPROPION (WELLBUTRIN)

Question 6

WHICH NON CYCLIC ANTIDEPRESSANT RARELY CAUSES SEIZ?

Answer 6

PROZAC

Question 7

WHICH NON CYCLIC ANTIDEPRESSANT CAUSES GI ISSUES ACUTELY AND NEURO S&S CHRONICALLY?

Answer 7

LITHIUM

Question 8

LITHIUM TX?

Answer 8

NS, Q2 HR LEVELS IF ACUTE (6 CHRONIC), TREND NA AND RENAL FUNC, DIALYSIS, NO AC (DOES NOT BIND)

Question 9

NAME MONOAMINE OXIDASE INHIBITORS.

Answer 9

MARPLAN, NARDIL, EMSAM, PARNATE

Question 10

MAOI+SSRI = ?

Answer 10

SS

Question 11

MAOI + SYMPATHOMIMETIC = ?

Answer 11

HTN CRISIS

Question 12

MAOI + TYRAMINE (BP MED) = ?

Answer 12

DISULFIRAM RX

Question 13

GIVE EXAMPLES OF NON CYCLIC ANTIDEPRESSANTS.

Answer 13

BUPROPION (WELLBUTRIN), DULOXETINE (PROZAC), LITHIUM, MAOI, SELECTIVE SEROTONIN REUPTAKE INHIBITORS, TRAZODONE (DESYREL), VELAFAXINE (EFFEXOR)

Question 14

NAME SELECTIVE SEROTONIN REUPTAKE INHIBITORS.

Answer 14

CELEXA, LEXAPRO, PROZAC, PAXIL, ZOLOFT, VIIBRYD, FLUVOXAMINE

Question 15

WHICH SELECTIVE SEROTONIN REUPTAKE INHIBITOR CAUSES >QRS AND QTC?

Answer 15

CELEXA

Question 16

WHICH SELECTIVE SEROTONIN REUPTAKE INHIBITOR CAUSES SEIZ RARELY?

Answer 16

LEXAPRO AND PROZAC

Question 17

WHICH SELECTIVE SEROTONIN REUPTAKE INHIBITOR CAUSES ANISCORIA (UNEQUAL PUPILS), CNS DEP, TREMORS, SIADH, HYPNATREMIA?

Answer 17

PAXIL

Question 18

WHICH SELECTIVE SEROTONIN REUPTAKE INHIBITOR CAUSES SEIZ RARELY, HTN, FEVER?

Answer 18

ZOLOFT

Question 19

WHICH SELECTIVE SEROTONIN REUPTAKE INHIBITOR CAUSES INCREASED LFTS, BRADY?

Answer 19

VIIBRYD

Question 20

WHICH NON CYCLIC ANTIDEPRESSANT CAUSES SEDATION, HTON, BRADY, RESP DEP, SEROTONIN SYNDROME, RARLEY SEIZ?

Answer 20

TRAZODONE (DESYREL)

Question 21

WHICH NON CYCLIC ANTIDEPRESSANT CAUSES TREMOR, SEIZ? SYM USUALLY DEVELOP?

Answer 21

VELAFAXINE (EFFEXOR), WITHIN 4 HRS

Question 22

NAME TWO ATYPICAL ANTIPSYCHOTICS.

Answer 22

CLONAZAPINE AND RISPERDAL

Question 23

WHICH ATYPICAL ANTIPSYCHOTIC CAUSES >AGRANULOCYTOSIS, MORE COMMONLY ASSOCIATED WITH DYSTONIC REACTION? HOW DO YOU TX DYSTONIC RX?

Answer 23

CLONAZAPINE; TX W/ DPH

Question 24

WHICH ATYPICAL ANTIPSYCHOTIC CAUSES TACHY, HTON, EPS, >QTC, SEIZ?

Answer 24

RISPERDAL

Question 25

NAME TYPICAL ANTIPSYCHOTICS.

Answer 25

HALDOL, MELLARIL, SERENTIL

Question 26

WHAT S&S DO TYPICAL ANTIPSYCHOTICS CAUSE?

Answer 26

MYOCARDIAL DEPRESSION

Question 27

PT PRESENTS 1 HR AFTER INGESTING UNKNOWN AMT OF AMITRIPTYLINE. SYM OF TCA OD?

• DRY MOUTH, HTN, URINARY RETENTION, TACHYCARDIA, SEIZ
• POLYURIA, POLYDIPSIA, HYPERNATREMIA, SEIZ
• SALIVATION, LACRIMATION, EXCESSIVE PULM SECRETIONS, SEIZ
• TEMP OF 104 DEGREES, AMS, OCULAR CLONUS, FAST BRISK LOWER EXTREMITY REFLEXES

Answer 27

-DRY MOUTH, HTN, URINARY RETENTION, TACHYCARDIA, SEIZ