Anticoagulant Drugs

Question 1

2 types of heparin?

Answer 1

Unfractionated

LMWH

Question 2

Action of heparin?

Answer 2

Unfractionated - potentiates Antithrombin

LMWH - inhibition factor Xa

Question 3

Is heparins action delayed or immediate?

Answer 3

Immediate

Question 4

How do u monitor heparin?

Answer 4

Unfractionated - ATPP

LMWH - doesn’t need monitored

Question 5

Complications of heparin use?

Answer 5

Bleeding
Heparin induced thrombocytopenia -HITT
Osteoporosis in long term use

Question 6

How do you reverse heparin ?

Answer 6

Stop heparin

Protamine sulfate

Question 7

Action of warfarin?

Answer 7

Vitamin k antagonist

Question 8

How do you monitor warfarin?

Answer 8

INR

Question 9

How do you reverse warfarin?

Answer 9

Omit warfarin dose
Oral vitamin k
Clotting factors - FFP or factor concentrates

Question 10

Speed of action of vitamin K?

Answer 10

6 hours

Question 11

Speed of action of clotting factors?

Answer 11

Immediate

Question 12

Action of dabigatran?

Answer 12

Direct thrombin inhibitor

Question 13

Action of rivaroxiban/ apixiban?

Answer 13

Direct activated factor X inhibitors

Question 14

Advantage of NOAC?

Answer 14

No monitoring required

Used first line Stoke prevention in AF and as prophylaxis after knee and hip surgery