Anti-TB drug list Flashcards
1
Q
what’s the name of the drug given as a “cocktail”
A
isoniazid
2
Q
Isioniazid:
Ses?
A
hepatotoxicity, minor peripheral neuropathy
3
Q
Rifampin:
SEs?
A
orange/brown urine and tears, nausea, anorexia, strong P450 inducer
4
Q
all anti-TBs have what gram acitivty?
A
gram +
5
Q
Rifabutin treats?
A
M. avium complex (MAC)
6
Q
difference b/w rifapentine and rifampin?
A
rifapentine dosed less frequently
7
Q
what’s unique about rifaximin?
A
not used for TB, treats traveler’s diarrhea caused by E. coli
8
Q
which drug is used synergistically with rifampin?
A
Ethambutol
9
Q
Ethambutol:
SEs?
not recommended for?
A
visual acuity/ red-green color discrimination
children who can’t read eye charts
10
Q
Pyrazinamide:
SEs?
A
hyperuricemia
11
Q
list all 2nd line anti-TBs
A
AGs: streptomycin, kanamycin, and amikacin Ethionamide Cycloserine Aminosalicylic acid Capreomycin FQs: levofloxacin and moxifloxacin