Anti-TB drug list Flashcards

1
Q

what’s the name of the drug given as a “cocktail”

A

isoniazid

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2
Q

Isioniazid:

Ses?

A

hepatotoxicity, minor peripheral neuropathy

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3
Q

Rifampin:

SEs?

A

orange/brown urine and tears, nausea, anorexia, strong P450 inducer

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4
Q

all anti-TBs have what gram acitivty?

A

gram +

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5
Q

Rifabutin treats?

A

M. avium complex (MAC)

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6
Q

difference b/w rifapentine and rifampin?

A

rifapentine dosed less frequently

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7
Q

what’s unique about rifaximin?

A

not used for TB, treats traveler’s diarrhea caused by E. coli

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8
Q

which drug is used synergistically with rifampin?

A

Ethambutol

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9
Q

Ethambutol:
SEs?
not recommended for?

A

visual acuity/ red-green color discrimination

children who can’t read eye charts

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10
Q

Pyrazinamide:

SEs?

A

hyperuricemia

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11
Q

list all 2nd line anti-TBs

A
AGs: streptomycin, kanamycin, and amikacin
Ethionamide
Cycloserine
Aminosalicylic acid
Capreomycin
FQs: levofloxacin and moxifloxacin
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