anatomy of aging Flashcards

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1
Q

what is ageing

A

‘the impact of the accumulation of a wide variety of molecular and cellular gamage over time’

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2
Q

growth in the cardiovascular system

A
  • increase in stroke volume
  • decrease in heart rate
  • increase in blood pressure
  • post natal circulatory changes
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3
Q

ageing in cardiovascular system

A
  • loss of elasticity to vessels
  • atherosclerosis
  • weakness of vessel walls
  • enlargement of heart
  • calcification and incompetence of heart valves
  • cardiac bridging
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4
Q

growth in respiratory system

A
  • inflammation of lungs at birth
  • descent of larynx
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5
Q

ageing in respiratory system

A
  • loss of elasticity
  • accumulation of particulates
  • damage to alveoli
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6
Q

growth in musculoskeletal system

A
  • development of cartilage models
  • gradual ossification of cartilage
  • fusion of epiphyses
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7
Q

ageing in muscoskeletal system

A
  • slowing of bone replacement
  • reduction in bone density
  • curvature of spine
  • osteoarthritis
  • degeneration of intervertebral discs
  • reduction of muscle mass
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8
Q

growth in nervous and sensory changes

A
  • largely in utero
  • synaptic remodelling in puberty
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9
Q

ageing in nervous and sensory changes

A
  • brain decreases in size
  • accumulation of cellular damage
  • lenses becoming cloudy - cataracts
  • retina degenerates
  • hearing loss
  • general loss of sensory acuity
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10
Q

growth in endocrine system

A
  • mostly in utero
  • thymus decreases in size from early childhood
  • gonads and mammary glands develop during puberty
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11
Q

ageing in endocrine system

A
  • atrophy of thymus functionally complete by 40
  • menopause - atrophy of ovaries, atrophy of mammary glands
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12
Q

effects of aging on digestive system

A
  • weakening of the wall
  • reduced peristalsis
  • distention
  • diverticulae
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13
Q

effects of ageing on integumentary system

A
  • loss of collagen
  • loss of elasticity in skin
  • loss of melanin in hair
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