ageing: cardiovascular system Flashcards

1
Q

major changes to blood vessels occurs due to

A

chronic inflammation

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2
Q

what casues the inner lining of our blood vessels to get damaged

A

micro insults

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3
Q

micro insults occur from

A

elevated blood pressue, high blood sugar, smoaking and other normal processes

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4
Q

body tries to repair micro insults with…

A

inflammation

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5
Q

repairng of micro insults in blood vessels

A

happens through atherosclerosis/ arteriosclerosis

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6
Q

process of athersclerosis or arterisclerosis

A
  • chronic inflammation causes release of more free radicals
  • body starts depositing chorlesterol filled cells into lining of cells
  • Chronic inflamation then changes the fatty streaks into fibrous plaques
  • plques can break off abd become blood clots or can narrow the artery into, blood cant get through
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7
Q

what happens to plaques formed in atherosclerosis

A
  • can break off and become blood clots: causing strokes, heart attack or deep vein thrombosis
    Or
    -can narrow the artery so blood cant get through causing ischemia
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8
Q

ischemia is:

A

decreased blood flow and is responsible for many ageing changes

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9
Q

sclerosis of blood vessels can cause: 8

A
  • hardened artery wallls, loose elasticiy and become less complient
  • more pressure - hypertesnsion
  • arteries can’t adjust to lower blood volume, causing orthostatic hypotension
  • pressure against heart from blood vessels makes heart grow more cells: hyperthrophy
  • cells grow outward and inward, decreases area for blood to collect, reducing cardiac output
  • ischemia to heart muscle can cause heart to beocme fibronic and harder
  • heart valves can calcify – they become hard and don’t close as well, letting blood flow the wrong way when the heart pumps.
  • the maximum heart rate that older adults can achieve is lower.
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10
Q

sclerosis casues artery walls to become:

A

hard, less elastic, less compliant

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11
Q

decreased compliance in artery walls leads to:

A

they dont bend and change well
generally casues more pressuer- hypertension

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12
Q

what happens to heart from sclerosis

A
  • pressure from blood vessels makes heart grow more cells- hypertrophy
    these cells grow outward and inward , dreasing area to collect blood , reducing cardiac output
    ischemia to heart muscle can cause the heart muscle ot become fibrotic
    heart valves can calcify allowing blood to pump wring way
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13
Q

hypertrophy=

A

heart grow more cells

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