adrenergic agonists

Question 1

guanabenz

Answer 1

direct A2 selective agonist

used as antihypertensive

diminish SNS outflow

Question 2

dobutamine

Answer 2

direct B1 selective agonist (also A1)

incresae CO with less reflex tach - lack of B2 stimulated venous dilation

Question 3

albuterol

Answer 3

direct beta 2 selective agonist

Question 4

clonidine

Answer 4

direct A2 selective agonist

used as antihypertensive

diminish SNS outflow

Question 5

methyldopa

Answer 5

direct A2 selective agonist

used as antihypertensive

diminish SNS outflow

Question 6

Ritodrine

Answer 6

beta 2 selective agonist

more selective for uterine SM - prevents labor

Question 7

prenalterol

Answer 7

direct B1 selective agonist

partial agonist -

incresae CO with less reflex tach - lack of B2 stimulated venous dilation

Question 8

terbutaline

Answer 8

direct beta 2 selective agonist

orally avalible - longer lasting

Question 9

methoxamine

Answer 9

direct A1 selective agonist

Question 10

phenylephrine

Answer 10

direct A1 selective agonist

not metabolized by COMT (not a catecholamine) = longer duration of action

can be used as decongestant

Question 11

oxymetazoline / xylometazoline

Answer 11

direct A1 selective agonist

used as topical decongestants

Question 13

salmeterol

Answer 13

direct beta 2 selective agonist

Question 14

guanfacine

Answer 14

direct A2 selective agonist

used as antihypertensive

diminish SNS outflow