AcidBase.Fluids.Lytes Articles 2017-2019 Flashcards
JVIM 2009 What was the incidence of hypoiCa in ciritally ill dogs and what was it associated with
16%
Associated with increased hospital stay, but not with survivial
JVIM 2009 Which dogs were more likely to have hypoiCa
renal failure, DKA, pancreatitis, sepsis
JVIM 2009 In trauma patients what was found to have worse ouctomes
acidosis and hypo iCa
JVECC 2008 How did the decrease in TP associated with an LRS 10 ml/kg/hr fluid bolus alter unmeasured anions
If use the prefluid TP did not alter unmeasured anions
JVIM 2017 What are the components of a balanced cyrstalloid
Contain species specific lytes concentrations
Maintain or normalize acid/base balance (appropriate SID)
Isosmotic and isotonic with plasma
Consider temperature dependence of H2CO3
JVECC 2017 Which fluid types did not support bacterial growth
Acetate and gluconate containing fluids
JVECC 2017 What percentaage of fluid bags had bacterial contamination
4.4 % of all bags (only positive were in ER setting)
30% of all ports
Did not alcohol ports as did not want to do extra measures to prevent contamination.
JVECC 2018 In all cause mortality what acid base status was highest
Lactic acidosis 59%, Dogs; 49% cats
In dogs hyperlactemia with normal acid/base increased mortality
Cat findings differ from previous study which showed no difference
AJVR 2018 How is diaslyte Na concentration compared to patient Na concetration
Diaslyate Na concentration correltated with patient Na concentration in dogs
The Diaslyate to pateitn gradient may be able to predict dysnatremias
***a change in pateint Na does not predict the magnitude of Na influx during diaslysis
JVECC 2018 How does NG tube suctions change acid base
It does not lead to a hyperchloremic metabolic alkalosis over a 36 hr period
NGT pH increased over time
JVIM 2018 How did a 6% tetrastarch compare to LRS in hemorrhaged anesthetized dogs for volume resuscitation in terms of extravascular lung volume
TS causes less extravascular lung water than LRS, neihter had evidence of pulmonary edema
JVIM 2018 How did a 6% tetrastarch compare to LRS in hemorrhaged anesthetized dogs for volume resuscitation in terms markers for AKI
Neither produced AKI as no change in plasma/urine NGAL or creatining or UNGAL/Crea ratio
AJVR 2019 in working dogs what was used to evaluate early dehdyration
Delayed skin turgor measured at the sagital crest able to detect mild dehydration evidence by loss of 0.83% body weight
CRT not as strongly correlated
AJVR 2019 How did a passive leg raise in pigs used to evaluate
Consistent with hypovolemia when raised at a 15 degree angle
Resulted in increase in cardiac output and decrease in pulse pressure variation
JVECC 2019 how did fluid resuscitation strategies alter NT Pro-BNP in healthy dogs
Did not increase above cardiac cut offs in healthy dogs receiving boluses of Norm-R, Hypertonic saline, or 6% tetrastarch 130/0.4
The Norm-R group remained above baseline longer
JVECC 2019 How is lactime defined
time in hours til lactate was > 2 mmol/L
JVECC 2019 What was noted in survivors vs non survivors evaluating lactate and shock index
Lactate clearance was higher in survivors at time 1 hr, 10 hrs, and 24 hours overall
Survivors shorter Lactime
JVECC 2019 Retro evaluation of K+ on prognosis in dogs and cats, what was found in prevelance and what increased mortality
Dogs, 27%, Cats 40 % abnormal K (up or down)
Increased mortality with Hypokalemia in dogs and hyperkalemia in cats
In dogs increased mortality compared to normal with mild hypo and hyperK
Urinary most likely to lead to hyperK
GI most likely to lead to hypoK
JVECC 2019 What is the pulse wave transit time
time from ECG R-wave peak to rise point of the pulse oximeter wave of the same cardiac cycle
The rise point is 30% of peak amplitude
Inversely porptional to SV and has a strong negative correlation with SV
JVECC 2019 What was the cut off for responders with pulse wave transit time
at a 3 ml/kg colloid bolus a -2.5% was a best fit cut off
There was a grey zone of -2.9 to -1.9
JVECC 2019 In a retro review how did creatinine and Cl change in anesthetized dogs receving 6% HES 670/0.7
Low creatinine conctrations post than pre
Higher chloride concetnrations post than pre
JVECC 2019 What are the systemic effects of hyper Cl-
altered renal blood flow, altered GFR, altered vascular resistance
JVECC 2019 how did CT of thorax correltate with blood gas and acid base findings in dogs
No acid/base correlation
Trauma found on CT correlated with abnormal A-a gradient and PaO2
JVECC 2019 How does hypoNa affect mortality
All causes higher mortality with hypo Na
Poor prognosis with CHF
JVIM 2019 How is VitD metabolism altered with Ca Oxolate stones
Subset of patients had decreased conversion of 25 OHD to 24,25 (OH)2D (inactive form Vit D)