9.9 Single Gene Inheritance 1 and 2 Flashcards
Tay-sachs disease is an example of what inheretence pattern?
autosomal recessive inheretence
in X-linked dominant inheretence, is a male is affected, what is the outcome of the daughter?
The daughters would definitely be affected. They inheret the X from their father.
autosomal dominance pattern of inheritance displays vertical inheritance, which means:
usually the phenotype appears in every generation
X-inactivation is a random event, so most females have the paternal X in ____ of their cells and maternal X in _____ of their cells. can this change?
half, half
yes, some females can have different proportions
neurofibromatosis shows _______ expression
variable
an all-or-none phenomenon. You either show features of the genotype or not at all. Even though they have the mutated gene, not everyone who has the gene gets the disease.
reduced penetrance
is there a gender bias in autosomal dominance pattern of inheritance?
no
in X-linked inheretence in general, can fathers pass on the disease to their sons?
NO
what type of inheretence pattern is this pedigree?
autosomal dominance pattern of inheritance
The position of a gene on a chromosome
locus
why do some females have milder or more severe phenotypes of X-linked diseases?
Lyon hypothesis - they have different proportion of active and in-active X-linked genes.
what pattern of inheretence is this?
autosomal recessive
in autosomal recessive inheretence, the parents of an affected individual are usually _______
unaffected
in X-linked recessive inheretence, an affected father will make all of his daughters what?
carriers. all of them recieve the x* from their dad
the finding that females express only one allele of their X-linked genes, although they actually have two. Ensures that females do not produce twice the gene product. What is this called?
dosage compensation