9.19 Membrane Properties - Carrier-Mediated Transport Flashcards

1
Q

saturability is a diagnostic characteristic of __________ transport

A

carrier-mediated transport

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2
Q

why is there saturability? (2)

A
  1. finite number of transporters

2. each transporter has finite turnover

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3
Q

what are the two diagnostic characteristics of carrier-mediated transport?

A
  1. saturability

2. selectivity

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4
Q

for carrier-mediated transport, flux is dependent on ___________. What is the equation for flux?

A

Jmax

J = (Jmax*[S])/(Kd + [S])

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5
Q

Kt is the substrate concentration at which ________________

A

half of the transporters are occupied

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6
Q

occurs when two or more substrates of a particular structure attempt to simultanously occupy the transporters. There is an increase in the Kt.

A

competitive inhibition

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7
Q

in competitive inhibition for a transporter, Kd is ________ and Jmax ___________

A

increased (takes more of original to half saturate)

stays the same

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8
Q

cocaine is an example of ________________ for serotonin

A

competitive inhibition

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9
Q

there is no ATP required in __________ __________ (membrane protein)

A

facilitated

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10
Q

CAN’T generate net flux against gradient:

A

facilitated diffusion

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11
Q

__________ __________ requires an energy source.

A

active transport

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12
Q

Develops and maintains transmembrane solute gradients

A

active transporters

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13
Q

in primary active transport, the immediate energy source is _______. in secondary active transport the immediate energy source is _______________.

A

ATP

existing trans-membrane ion gradients

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14
Q

the most common ion whose gradient is tapped into is ______

A

Na+

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15
Q

the inside of a cell has _______ K+ and _____ Na+

A

high K+

low Na+

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16
Q

what is an example of co-transport?

A

Na+/glucose transporter, uses Na+ concentration gradients to get glucose into the cell.